Rosuvastatin Calcium 10mg Tablet

Adult dosage

Regardless of meals, start with an initial dose of 5 mg once daily. If further LDL cholesterol reduction is needed, the maintenance dose is adjusted, with most patients being controlled at 10 mg once daily. The maintenance dose should be adjusted every 4 weeks or longer based on LDL cholesterol levels, treatment goals, and patient response, with a maximum daily dose of 20 mg.

Children's dosage

Pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia should receive a dose ranging from 5 mg to 20 mg once daily. The dosage should be adjusted based on individual treatment goals with a minimum interval of 4 weeks.

This medication should not be used in certain patients. For example, individuals who are allergic to any ingredient of this medication, those with severe liver dysfunction, or those with muscle diseases should not take this medication. Furthermore, individuals with severely impaired renal function, pregnant or nursing women, and fertile women who are not using adequate contraception should also avoid this medication. This medication contains lactose, making it unsuitable for those with lactose intolerance or certain genetic metabolic disorders. This medication may affect liver function, so individuals who consume large amounts of alcohol or have a history of liver disease should have liver function tests before use and exercise caution. Muscle-related side effects like myalgia or myopathy may occur, thus any symptoms such as muscle pain, weakness, or cramps should be reported to a doctor immediately. Precautions are especially necessary for those with compromised renal function, hypothyroidism, a history of muscle diseases, or the elderly. This medication can rarely cause serious skin reactions or liver damage; if any symptoms such as skin rash, jaundice, or severe fatigue occur, the medication should be stopped immediately and medical advice should be sought. This medication may interact with other drugs, so if you are taking other medications, you must inform your doctor or pharmacist. Specifically, the risk of muscle side effects may be increased when used in conjunction with certain antivirals, immunosuppressants, antifungals, some antibiotics, or fibrates. Women who are pregnant or planning a pregnancy should not take this medication, and if pregnancy occurs while taking it, it should be stopped immediately. Nursing women are also advised to avoid this medication. In case of overdose, there is no specific antidote, so treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored regularly. Caution should be exercised when driving or operating machinery, as dizziness may occur. This medication can be used in children and adolescents, but limited information is available regarding its effects on growth and secondary sexual characteristics, so it should be used with caution.

Serious side effects

Hives, angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, liver failure, hyperbilirubinemia, severe muscle weakness, ocular myasthenia, rhabdomyolysis, acute renal failure, oliguria, severe edema, thrombocytopenia, severe allergic reactions, severe skin adverse reactions, respiratory distress, serious neurological symptoms

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication should be kept in a tightly closed container to avoid exposure to air or moisture, and it is best stored at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance

Pink round film-coated tablet

Package unit

28 tablets per box [28 tablets (14 tablets/PTP x 2)]