Moxikra Tablet 375 mg

Adult dose

Adults and children 12 years or older, or weighing over 40 kg, take amoxicillin/clavulanate potassium at 250 mg/125 mg orally three times a day every 8 hours, and in cases of severe and respiratory infections, the dosage may be increased to 500 mg/125 mg per dose. In cases of renal impairment, adjust according to creatinine clearance as follows: - Creatinine clearance over 30 mL/min: dosing adjustments are not necessary.

Child dose

For children ages 12 and older or weighing 40 kg or more, the same dosage as adults is used. In children with renal impairment, the dosage should be reduced in the same manner as for adults.

This medication should not be administered to certain patients. For example, patients who are allergic to the ingredients of this medication or have experienced hypersensitivity reactions to beta-lactam antibiotics should not take this medication. Patients with viral infections such as infectious mononucleosis or lymphocytic leukemia should also avoid this medication. Patients who have had liver dysfunction or jaundice due to this medication or penicillin-related drugs in the past should not use it. Patients with impaired liver function should use this medication with caution. Patients with moderate to severe kidney impairment may also need to adjust the dosing interval as the drug concentration in the blood may increase. Patients with an allergic constitution or those who have symptoms of bronchial asthma, skin rashes, etc., should take this medication cautiously. Additionally, patients who have difficulty with oral intake, elderly patients, or those with poor general health may show symptoms of vitamin K deficiency, so caution is required. Patients with gastrointestinal symptoms like vomiting or diarrhea may have impaired drug absorption and should be cautious. While taking this medication, a variety of side effects may occur. Gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain are common, and serious problems such as gastritis or acute pancreatitis may rarely occur. Liver function abnormalities have also been reported, especially more frequently in elderly men, and caution should be observed with prolonged use. Skin reactions such as itching, rashes, and in severe cases, serious skin reactions like Stevens-Johnson syndrome may occur, so if any unusual symptoms arise, the medication should be discontinued immediately. Blood-related side effects such as leukopenia or thrombocytopenia have been reported rarely. In the central nervous system, headaches, dizziness, and seizures may rarely occur, and patients with poor kidney function may be at risk of renal failure. This medication may interact with other drugs, so if you are taking other medications, you must inform your doctor or pharmacist. Special caution is needed when used in combination with drugs that affect blood coagulation, certain antibiotics, or anticancer drugs. This medication may reduce the effectiveness of oral contraceptives, so this should also be taken into consideration. Women who are pregnant or may become pregnant should consult a doctor before taking this medication. Especially during the first three months of pregnancy, it is advisable not to use this medication, and breastfeeding women should also be cautious as the medication may be transmitted in breast milk, potentially causing diarrhea or allergic reactions in the baby. For children, it is only recommended for those over 12 years of age or weighing over 40 kg, as there is less usage experience for younger children. Elderly patients may experience side effects more easily due to decreased bodily functions, so the dosage and dosing intervals should be adjusted while closely monitoring their condition. In case of overdose, gastrointestinal symptoms may primarily occur, but there may also be rare cases of kidney dysfunction or neurological abnormalities, so if symptoms appear, immediate discontinuation and medical assistance is necessary. This medication should be stored in a sealed container to prevent moisture, and it is advised to store it in a cool place between 1 degree and 25 degrees. Proper storage will help maintain the medication's efficacy and safety.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty in breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of the skin or eyes, extreme fatigue, liver abnormalities, sudden and severe headaches, thunderclap headache, seizures, altered consciousness.

Mild side effects

Diarrhea, pseudomembranous colitis, indigestion, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal distension, constipation, colonic pain, hyperacidity, soft stools, dry mouth, acute pancreatitis, candidiasis, antibiotic-associated colitis, bloody stools, itching, erythema multiforme, mucous membrane syndrome, toxic epidermal necrolysis, vesiculobullous dermatitis, acute generalized exanthematous pustulosis, eosinophilia, fever, rash, arthralgia, edema, lymphadenopathy, vasculitis.

This medication should be kept in a sealed container to prevent moisture, and it is best stored in a cool, dry place at temperatures between 1 and 25 degrees. This way of storage helps maintain the medication's efficacy and safety.

Appearance

It is a white or nearly white oval film-coated tablet.

Package unit

100 tablets (10 tablets/PTPX10)