Alezin Tablet 20 mg (Epinastrine Hydrochloride)

Adult dose

Asthma, urticaria, eczema/dermatitis, pruritus, prurigo, and common psoriasis accompanied by pruritus Adults: Administer 20 mg of epinastine hydrochloride orally once daily. Adjust the dose as appropriate according to symptoms. Allergic rhinitis Adults: Administer 10～20 mg of this medicine orally once daily. Adjust the dose as appropriate according to symptoms.

This medication should not be used by patients who have an allergic reaction to this drug or any components of this drug. This medication contains lactose and should not be taken by patients with genetic diseases that affect lactose digestion. Patients with liver disease or a history of liver disease should use this medication with caution as liver function may deteriorate. If any allergic symptoms such as rash, urticaria, swelling of the face or extremities, or pruritus occur during use of this medication, discontinue use immediately and consult a doctor. Occasionally, neurological symptoms such as drowsiness, fatigue, headache, dizziness, insomnia, and nightmares may occur, so be cautious. Gastrointestinal symptoms such as nausea, abdominal pain, dry mouth, diarrhea, and constipation may occur, so report any abnormal symptoms. There may be liver function abnormalities, so it is recommended to have regular liver function tests, and if jaundice or symptoms of hepatitis occur, discontinue use immediately. This medication may affect kidney function, and proteinuria may occur, so caution is required. Symptoms similar to cystitis such as frequent urination, hematuria, or urinary retention may occur, so report any abnormalities. Rapid heartbeat symptoms may appear, so be cautious. Respiratory symptoms such as shortness of breath and nasal congestion may rarely occur. Blood tests may show thrombocytopenia or leukocytosis, so report any unusual symptoms to a physician. In females, symptoms such as gynecomastia, menstrual irregularities, and breast pain may rarely occur. This medication is not a rapid relief medication for asthma attacks, so it is important to explain this to asthma patients. For patients taking long-term corticosteroids, the steroid dosage should be gradually adjusted when taking this medication. This medication may cause drowsiness, so caution is needed when driving or operating machinery. If there are no therapeutic effects, it is advisable not to use it for prolonged periods. Patients with seasonal allergies should start taking this medication before symptoms begin and continue until symptoms subside. When combined with other sedatives or alcohol, there may be an enhanced sedative effect, although the risk is low; caution should still be exercised due to limited experience. This medication has a low risk of drug interactions with other drugs metabolized in the liver. Safety during pregnancy has not been established, so women who are pregnant or may become pregnant should consult a physician before use. Nursing mothers should avoid this medication if possible, or discontinue breastfeeding as it can be passed into breast milk. Safety for children, especially low birth weight infants or young children, has not been adequately confirmed. Elderly patients often have impaired liver and kidney function, which may increase the risk of adverse reactions, so regular observation of their condition and dosage adjustments if needed are recommended. Overdose may cause arrhythmias or other heart abnormalities, so if symptoms are suspected, immediate medical assistance is required. Overdose may require treatments such as gastric lavage or urinary induction. This medication should be stored out of reach of children, and transferring to another container is not good for maintaining quality. Taking the medication on an empty stomach may increase blood concentration, so adjusting the intake timing according to the condition is advisable.

• Allergic reactions
• rash
• hives
• erythema
• itching
• edema
• erythema accompanied by itching
• drowsiness
• malaise
• headache

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is also recommended to store it at room temperature between 1°C and 30°C. By storing it this way, the effectiveness of the drug can be safely maintained.

Appearance

White or pale yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle