Keenastin Tablets 20 mg (Epicastine Hydrochloride)

Adult dose

1. Asthma, urticaria, eczema/dermatitis, pruritus, pruritic eruptions (prurigo), and common psoriasis accompanied by pruritus Adults: Administer 20 mg of epinastine hydrochloride orally once daily. Adjust the dose as appropriate according to symptoms. 2. Allergic rhinitis Adults: Administer 10～20 mg of this medicine orally once daily. Adjust the dose as appropriate according to symptoms.

This drug should not be used in patients who are allergic to this medication or its components. It contains lactose, therefore patients with genetic issues like galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take it. Patients with liver diseases or a history of liver diseases should be cautious as their liver condition may worsen when using this drug. If allergic symptoms such as rash, hives, or swelling of the face or extremities occur during treatment, stop taking this medication immediately and consult a doctor. Rare neurological symptoms such as drowsiness, headache, dizziness, insomnia, and nightmares might occur, so caution is advised. Gastrointestinal symptoms like indigestion, nausea, abdominal pain, diarrhea, or constipation may occur, so any unusual symptoms should be reported. Liver function abnormalities may be noted; therefore, liver function test results should be closely monitored, and if abnormalities are found, the medication should be discontinued. Rare renal and urinary symptoms such as proteinuria, frequent urination, and hematuria may occur, so careful observation is necessary. Symptoms such as palpitations, shortness of breath, and nasal congestion may rarely occur. Blood tests may show thrombocytopenia or leukocytosis, so regular testing is required. Symptoms such as gynecomastia, menstrual irregularities, or chest pain may occur rarely. This medication is not intended for quick relief of asthma attacks, so the purpose and effects for asthma patients should be sufficiently explained. Patients undergoing long-term steroid treatment should gradually reduce their steroid intake when taking this drug and must follow their doctor's instructions. Caution is needed when operating machinery or driving, as drowsiness may occur. If there is no effect, it is advisable not to take it for a long time. Patients with seasonal allergies are recommended to start taking it before symptoms begin and continue until symptoms resolve. This medication is unlikely to enhance sedation when taken with other sedatives or alcohol, but caution is necessary as experience with co-administration is limited. This medication is primarily excreted via the kidneys and is not metabolized in the liver, so the risk of interaction with other drugs is low. Safety during pregnancy is uncertain, so women who are pregnant or may become pregnant should administer it only after consulting with a physician. Women who are breastfeeding should avoid taking this drug or discontinue breastfeeding, as it may be excreted in breast milk. Safety in children, especially in low-birth-weight infants, newborns, and infants has not been sufficiently established. Elderly patients may have reduced liver and kidney function, so unusual symptoms should be closely monitored, and dosages may need to be reduced or medication discontinued if necessary. Overdose may lead to cardiac abnormalities such as arrhythmias, so if overdose is suspected, immediate ECG monitoring and appropriate treatment should be sought. This medication should be kept out of the reach of children and should not be transferred to other containers. Taking it on an empty stomach may increase blood concentration, therefore, it is recommended to take it before bedtime or after meals depending on symptoms.

Allergic reactions (rash, hives, redness), itching, swelling (face, extremities, etc.), erythema with itching, drowsiness, lethargy, headache, dizziness, insomnia, nightmares, numbness, feeling of heaviness in the head, nausea, abdominal discomfort, thirst, abdominal pain, loss of appetite, vomiting, feeling of unease in the stomach, sense of fullness in the stomach, diarrhea, constipation, dry lips, abdominal distension, stomatitis, liver dysfunction (elevated AST, ALT, γ-GTP, ALP, LDH), jaundice, hepatitis, proteinuria, increased urinary frequency, hematuria, urinary retention, palpitations, dyspnea, difficulty expectorating, nasal congestion, thrombocytopenia, leukocytosis, gynecomastia, breast enlargement, menstrual irregularities, flushing, bitter taste, taste disturbance, chest pain

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius to preserve the drug's efficacy.

Appearance

White or pale yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle