Celemin Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks a day, so it should be discussed with a doctor or pharmacist. This medication may also increase the risk of cardiovascular thromboembolic events, myocardial infarction, and stroke, with the risk potentially increasing with the dosage and duration of treatment. Even in patients without a history of cardiovascular disease, cardiovascular symptoms should be closely monitored when taking this medication, and immediate action should be taken if symptoms like chest pain or shortness of breath occur. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal perforation, ulcers, and bleeding, especially in the elderly, where the risk may be higher. If signs of gastrointestinal bleeding such as epigastric pain, indigestion, black stools, or hematemesis occur, medical attention should be sought immediately. This medication should not be administered to those with a specific history of allergies, severe liver disease, kidney disease, active gastric ulcer, congestive heart failure, or pregnant women. Patients with liver or kidney dysfunction, or a history of asthma, hypertension, and heart failure should use this medication with caution and require regular monitoring. Various adverse reactions including headaches, dizziness, indigestion, skin rashes, edema, hypertension, and dyspnea may occur, so it is advisable to consult medical professionals if symptoms arise. This medication may affect liver and kidney function, thus regular blood testing and liver and kidney function tests are recommended during use. Women who are pregnant or may become pregnant should not take this medication, and it should also be avoided during breastfeeding. This medication may interact with other drugs, so if you are taking any medications, you must inform your doctor or pharmacist. When taking this medication, use the lowest effective dose possible and minimize the treatment duration to reduce cardiovascular and gastrointestinal risks. Since dizziness or drowsiness may occur, caution should be exercised while driving or operating machinery. This medication has not been established for safety and efficacy in children and adolescents, hence it is not recommended for use in these populations. Elderly individuals may have a higher risk of decreased kidney and liver function, so additional caution is required, and dosage adjustments may be necessary. In case of overdose, symptoms such as lethargy, drowsiness, nausea, and vomiting may occur, and immediate medical attention should be sought.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, incontinence, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, elevated NAG, positive urine hematuria, positive urine protein, renal impairment, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of smell, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash (DRESS), acute generalized exanthematous pustulosis (AGEP), exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, menstrual disorders, chest pain, dyspepsia, diarrhea, headache, dizziness, constipation, gastric ulcer, urticaria, anemia, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, chest pain, hyperlipidemia, diabetes, weight gain, fracture, arthralgia, positive RA factor, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss

This medication should be stored in a tightly closed container to prevent the ingress of air or moisture, and it is advisable to maintain the storage temperature between 15 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and safety.

Appearance

A white to light yellow powder filled in white capsules with blue stripes on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle