Medication info
Limapera Tablets (Limaprost Alpha-Dex)

Limapera Tablets (Limaprost Alpha-Dex)

Prescription medicationTablet
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
Genupharm Co., Ltd.
Appearance
White round tablets
Packaging
84 tablets/Alu-Alu (21 tablets/Alu-Alu X 4)
Approval status
Active

MFDS item code 201901295 · Approved 2019.02.28 · Insurance code 698004020

Summary

Main use
Improvement of symptoms and walking ability in lumbar spinal stenosis, and ischemic symptoms of Buerger's disease
Who uses it
Adults
Adult dosage
1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted as appropriate according to age and symptoms.

Ingredients

Manufacturer
Genupharm Co., Ltd.

Efficacy & effects

Improvement of symptoms and walking ability in lumbar spinal stenosis, and ischemic symptoms of Buerger's disease

  • Ulcers
  • pain
  • cold sensations
  • lower limb pain
  • lower limb numbness
View approved original text

This medication helps alleviate ischemic symptoms such as ulcers, pain, and cold sensations due to thromboangiitis obliterans. It also relieves lower limb pain and numbness symptoms in patients with acquired lumbar spinal stenosis, and improves walking ability. Therefore, it is used to improve the uncomfortable symptoms caused by these conditions.

Dosage and Administration

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted as appropriate according to age and symptoms.

Precautions

This medication should not be used in women who are pregnant or may become pregnant. This medication contains lactose, so it should not be administered to patients with hereditary diseases that affect lactose digestion. Caution should be exercised for patients at risk of bleeding or patients taking medications that affect blood coagulation. Allergic reactions such as skin rash or itching may occur from using this medication, so it should be discontinued immediately if such symptoms arise. Bleeding may rarely occur, so symptoms should be closely monitored, and administration should be stopped if abnormalities are observed. Gastrointestinal disturbances may present as diarrhea, nausea, abdominal pain, decreased appetite, or heartburn, so caution is advised. It may affect liver function, and liver enzyme levels may rise, so it's important to check liver health status. Symptoms such as rapid heartbeat or low blood pressure may occur, so the patient's condition should be closely monitored. Various side effects can occur, including headache, facial flushing, dizziness, heat sensation, trembling, edema, and anemia. In patients with lumbar spinal stenosis, the decision to continue medication should be based on changes in symptoms. The effectiveness of this medication is not certain for severe spinal stenosis, so other treatments should be considered if surgery is necessary. Safety during pregnancy has not been established, and uterine contractions have been reported in animal studies, so avoid use during pregnancy. Safety in children has not been confirmed, so it is advisable not to use it in pediatric patients. Elderly patients may have decreased bodily functions, so the dosage should be adjusted or used cautiously. Administering large amounts to healthy adults may temporarily lower blood pressure, so avoid overdose.

Side effects

  • Rash
  • itching
  • hemorrhage
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • increased AST (GOT)
  • increased ALT (GPT)
  • palpitations
  • peripheral cyanosis
  • hypotension
  • headache
  • facial flushing
  • dizziness
  • heat sensation
  • generalized fatigue
  • edema
  • mastitis
  • trembling
  • hirsutism
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to prevent exposure to air and light. Additionally, it is important to maintain a room temperature of 1 to 30 degrees Celsius when storing the medication. This will help maintain the drug's efficacy for a longer period.

Appearance and packaging

Appearance

White round tablets

Package unit

84 tablets/Alu-Alu (21 tablets/Alu-Alu X 4)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.