Celebrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, another treatment should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg; if needed, an additional 200 mg may be administered on the first day of treatment. Starting on the second day, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding if taken by individuals who consume large amounts of alcohol daily, so consultation with a doctor or pharmacist is essential. This medication may increase the risk of cardiovascular issues such as heart attack or stroke, so it should be used at the lowest effective dose for the shortest duration. As there is a possibility of developing ulcers or bleeding in the gastrointestinal tract, patients with a history of gastrointestinal disorders should use caution and notify healthcare professionals immediately if symptoms occur. There are patients who should not take this medication, including those with allergic reactions, severely impaired liver or kidney function, and women who are pregnant or breastfeeding. Patients with weakened liver or kidney function, asthma, or hypertension should use this medication with caution, and their condition should be monitored frequently during administration. Common side effects during treatment may include dyspepsia, diarrhea, headache, dizziness, skin rash, and hypertension. If serious abnormal symptoms occur, immediate consultation with healthcare professionals is necessary. This medication may interact with multiple drugs, so if other medications are being taken, it is important to inform a doctor, especially when taking with antihypertensives, anticoagulants, and antidepressants. Women who are pregnant or planning to become pregnant should avoid this medication, and nursing mothers should either cease breastfeeding or discontinue the medication. It is advisable not to use in children or adolescents as safety and efficacy have not been established. Elderly patients may have impaired kidney and liver function, so dose adjustment and monitoring of condition are necessary. Regular blood tests and assessments of liver and kidney function should be carried out during treatment, and any abnormal findings should be reported to healthcare professionals immediately. As dizziness or drowsiness may occur while taking this medication, it is safer to avoid driving or operating machinery. In case of overdose, symptoms may include nausea, vomiting, drowsiness, and gastrointestinal bleeding, necessitating immediate medical attention.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, dyspepsia, diarrhea, irritable bowel syndrome, increased bowel movement frequency, abdominal pain, epigastric pain, bloating, nausea, constipation, diverticulitis, dysphagia, belching, esophagitis, gastroenteritis, gastrointestinal ulcer, gastroesophageal reflux, discomfort in the stomach, gastrointestinal disorders, hemorrhoids, hiatal hernia, bloody stools, dry mouth, stomatitis, back pain, dental disease, vomiting, exacerbation of gastrointestinal inflammation, angular stomatitis, intestinal obstruction, intestinal perforation, gastrointestinal bleeding, hemorrhagic colitis, esophageal perforation, pancreatitis, intestinal obstruction, alveolar osteitis after tooth extraction, enteral anastomotic ulcer, melena, glossitis, aphthous stomatitis, oral mucosa blister formation, diminished sensation in the mouth, oral pain, headache, dizziness, leg cramps, increased tension, sensory disturbances, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, peripheral edema, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, insomnia, anorexia, anxiety, increased appetite, depression, neurogenic response, drowsiness, fatal intracranial hemorrhage, delirium, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, petechiae, rash, alopecia, dermatitis, nail disease, photosensitivity reaction, itching, erythematous rash, maculopapular rash, skin diseases, dry skin, increased sweating, urticaria, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, worsening hypertension, angina, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, increased ALT, increased AST, elevated γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, hepatic failure, fulminant hepatitis, hepatic necrosis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopenia, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic esophagitis, contact dermatitis, injection site reaction, skin nodules, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, bile stasis, bile stasis hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rash, exfoliative dermatitis, renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, mesangial glomerulonephritis, menstrual disturbances, female infertility.

This medication should be stored in a tightly closed container to prevent air from entering and kept at room temperature between 15 and 30 degrees Celsius. This will help maintain the medication's effectiveness and prevent degradation.

Appearance

Capsules that are white with yellow stripes filled with a white to light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle