Prucaloprid 1 mg (Prucalopride Succinate)

Adult dose

This medication is administered orally and can be taken at any time of day regardless of meals. Adults: Once daily 2 mg Elderly patients (aged 65 and older): Initial dose is once daily 1 mg, which can be increased to once daily 2 mg if necessary. Patients with renal impairment: For patients with severe renal impairment (GFR < 30 ml/min/1.73 m2), administer once daily 1 mg; dosage adjustment is unnecessary for mild to moderate renal impairment.

This medication may not be administered to certain patients. For example, individuals allergic to the active ingredient or excipients of this medication, patients with severely impaired kidney function, and patients with serious intestinal inflammation or obstruction should not use this medication. Additionally, patients with a genetic condition that prevents the breakdown of lactose should also avoid taking this medication. In patients with severe renal impairment, the dosage of this medication must be reduced and used with caution. Patients with other serious conditions affecting the liver, heart, lungs, or nervous system should be especially cautious when using this medication. Precautions are particularly important for patients with a history of arrhythmias or ischemic heart disease. The most common side effects experienced when taking this medication include gastrointestinal symptoms such as headaches, abdominal pain, nausea, and diarrhea. These symptoms usually occur early in treatment and tend to resolve naturally over time. Other possible symptoms include dizziness, fatigue, and palpitations. If palpitations worsen, it is advisable to consult a physician. Due to limited usage experience during pregnancy, this medication is not recommended, and women of childbearing age should use effective contraceptive methods while taking it. Lactating women are also advised not to take this medication. This medication is generally not recommended for children or adolescents under 18 years of age. In case of overdose, symptoms such as headache, nausea, and diarrhea may appear, and since there is no specific antidote, appropriate treatment must be administered based on the symptoms. Electrolyte supplementation may be required in cases of dehydration due to diarrhea or vomiting. Caution is warranted when driving or operating machinery on the first day of taking this medication due to possible dizziness or fatigue.

Serious side effects

• Palpitations (heart palpitations)
• ventricular extrasystole
• chest discomfort

Mild side effects

Headache, gastrointestinal symptoms (abdominal pain, nausea, diarrhea), dizziness, tremors, palpitations, vomiting, dyspepsia, rectal bleeding, bloating, abnormal bowel sounds, frequent urination, fatigue, fever, malaise, dyspepsia, abdominal distension, abdominal discomfort, gastroesophageal reflux disease, rectal pain, hemorrhoids, functional gastrointestinal disorders, soft stools, esophagitis, duodenal ulcers, nasopharyngitis, bronchitis, herpes zoster, athlete's foot, bacterial vaginosis, bacterial bronchitis, face edema

This medication should be stored in a container that prevents light and air exposure, avoiding humid areas and keeping it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance

White to off-white round film-coated tablets

Package unit

28 tablets (14 tablets/Alu-Alu x 2)