Constipation Tablet 2 mg (Prucalopride Succinate)

Adult dose

This medication is administered orally and can be taken at any time of the day, regardless of meals. Adults take 2 mg once daily. Elderly patients aged 65 and older should take 1 mg once daily as the initial dose and may increase to 2 mg once daily if needed. For patients with severe renal impairment, 1 mg should be administered once daily, while dosage adjustment is not necessary for mild to moderate renal impairment. Patients with severe liver impairment

This medication should not be used in certain patients. Individuals allergic to the active ingredient or additives in this medication should not take it. Patients with severely impaired kidney function requiring dialysis should also not use this medication. It is not suitable for patients with structural or functional problems in the intestines or those with severe inflammation. Additionally, individuals with genetic metabolic disorders such as lactose intolerance should not take this medication. Patients with severe kidney impairment should use this medication with caution and a reduced dose. Safety in patients with serious conditions affecting the liver, heart, lungs, or nervous system has not been sufficiently confirmed, so caution is advised. Especially, patients with a history of arrhythmia or ischemic heart disease should be cautious when using this medication. Patients with very poor liver function should also use a reduced dose, and mild liver dysfunction is reported to have little impact. Caution is needed when this medication is used in conjunction with drugs that prolong the QT interval related to heartbeats. Common side effects of this medication include headache and gastrointestinal disturbances such as abdominal pain, nausea, and diarrhea. These symptoms typically occur early in treatment and usually resolve within a few days. Other reported side effects include dizziness, tremors, palpitations, fatigue, and frequent urination. If new palpitations occur, it is essential to consult a doctor. In the case of severe diarrhea, the effectiveness of oral contraceptives may be reduced, so it is advisable to use additional contraceptive methods. This medication has a low potential for interactions with other drugs; however, careful monitoring is necessary when used with specific medications, as blood concentration levels may change. Special caution is advised when used with heart-affecting medications, and drugs like atropine may reduce the effectiveness of this medication. Use of this medication during pregnancy is not recommended, and women of childbearing age should use effective contraceptive methods while taking it. Its use is also not recommended for breastfeeding women. It is advisable not to give this medication to children or adolescents under 18 years of age. In cases of overdose, symptoms such as headache, nausea, and diarrhea may occur, and appropriate treatment is necessary based on the symptoms. Dehydration and electrolyte loss may occur due to diarrhea and vomiting, so replenishment may be needed. This medication may cause dizziness or fatigue at the start of treatment, so caution is advised when driving or operating machinery.

Serious side effects

Chest discomfort

Mild side effects

• Headache
• dizziness
• tremors
• palpitations
• nausea
• diarrhea
• abdominal pain
• vomiting
• dyspepsia
• rectal bleeding

This medication should be stored in a closed container that protects it from light and should be kept dry. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (7 tablets/ Alu-Alu PTP packaging x 4)