Roxithromycin Tablet (Roxithromycin)

Adult dose

(Tablets) Adults: Administer 150㎎ (potency) of roxithromycin orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose appropriately according to age and symptoms.

Child dose

(Pediatric tablets)(Granules)(Suspension) Children: The mean dose used in clinical trials was 6mg (potency) per kg of body weight per day. This medicine is administered orally in 2 divided doses of 5～8mg (potency) per kg of body weight per day; doses according to body weight are as follows. Children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 2.5mL per dose twice daily before meals (suspension only). Children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 5mL per dose twice daily before meals (suspension only). Children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 10mL per dose twice daily before meals (suspension only).

This medication can cause severe skin conditions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. If symptoms such as blistering or mucosal damage appear, use should be discontinued immediately. It should not be administered to patients with hypersensitivity to this medication or those taking certain cardiovascular drugs, especially to patients with poor liver function or elderly patients who should use it with caution. Since it may affect heart rhythm, patients with a congenital heart conduction issue or those at risk of arrhythmia should be especially careful when using this medication. This medication can rarely cause severe allergic reactions or blood disorders, liver dysfunction, gastrointestinal issues, pneumonia, neurological symptoms, sensory disturbances, hearing or vision impairments, among various side effects. With prolonged use, there is a risk of resistant bacteria and secondary infections; thus, the patient's condition should be constantly monitored, and if symptoms worsen or abnormal symptoms arise, immediate consultation with healthcare providers is necessary. Patients with impaired liver function should undergo regular liver function tests and adjust the dosage as needed, while patients with poor kidney function do not require separate dosage adjustments. This medication may interact with other medications, so it is essential to inform healthcare providers if taking specific antihistamines, antiarrhythmics, anticoagulants, immunosuppressants, sedatives, or cardiac drugs. Pregnant women or those who could become pregnant should carefully consider the necessity and risks of using this medication, as it may affect the fetus. Nursing mothers should either avoid its use or discontinue breastfeeding if possible. Elderly patients do not require separate dosage adjustments, but caution is advised as the drug's half-life may be prolonged. This medication may cause dizziness or visual impairments, so caution is advised when operating machinery or driving. Lastly, store this medication out of reach of children, and do not transfer it to another container, as these practices are essential for maintaining the quality of the drug.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized pustular rash, shock, anaphylactic shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, increased serum bilirubin, loss of appetite, nausea, vomiting, gastrointestinal discomfort, dyspepsia, stomach pain, abdominal pain, abdominal bloating, diarrhea, membranous colitis, loose stools, hemorrhagic colitis, bloody stools, pancreatitis, bronchospasm, cough, dyspnea, abnormal chest X-ray findings, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, dysgeusia, ageusia, olfactory disturbances, loss of smell, erythema multiforme, purpura, superinfection due to overgrowth of non-susceptible pathogens, temporary hearing loss, hearing impairment, visual disturbances, blurred vision, conjunctival injection, generalized malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, nosebleeds, menstrual irregularities, inflammation of the oral and vaginal mucosa, hallucinations, confusion

This medication should be stored in a tightly sealed container to prevent air from entering, ideally at a temperature between 1 to 30 degrees Celsius (34 to 86 degrees Fahrenheit). This ensures the efficacy of the drug is maintained for a longer period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle