Cabalin CR Extended-Release Tablet 300 mg (Pregabalin)

Adult dosage

This medication should be taken once daily after dinner. A starting dose of 150 mg once daily may be administered. Based on individual patient response and tolerability, the dose can be increased to a maximum of 600 mg once daily at weekly intervals. When discontinuing, it should be tapered off gradually over a period of at least one week.

This medication acts on the central nervous system and may cause mental health issues such as depression or suicidal thoughts, so careful observation for such symptoms is necessary during treatment. Patients with hypersensitivity or allergy to any components of this medication should avoid it. Diabetic patients may experience weight gain from this medication, which can affect blood sugar control, thus requiring adjustments in their antidiabetic medication dosages. If symptoms of angioedema such as swelling around the face or mouth occur, the use of this medication should be stopped immediately. Elderly patients may experience side effects such as dizziness, drowsiness, or loss of consciousness more commonly, hence caution is required at the start of treatment. Blurry vision or changes in vision may occur, and these symptoms may improve upon discontinuation of the medication. Abruptly stopping this medication may lead to withdrawal symptoms such as insomnia, headache, or anxiety, hence dosage should be adjusted according to the physician's directions. There is a risk of drug abuse, so patients with a history of substance abuse should be particularly cautious and monitored for signs of abuse. Patients with reduced kidney function may need dosage adjustments for this medication. Patients with severe heart disease should exercise caution when using this medication. When taken in conjunction with opioid analgesics, there is an increased risk of central nervous system depression, potentially leading to serious side effects such as respiratory distress, so caution is warranted. In early pregnancy, there is a risk of fetal malformations, making it crucial for women who are pregnant or planning to become pregnant to consult a physician and employ effective contraceptive methods. During breastfeeding, this medication can be transmitted through breast milk and may affect infants, thus breastfeeding should be discussed with a physician. Dizziness and drowsiness may occur during treatment, hence it is advisable to avoid dangerous activities such as driving or operating machinery until familiar with the medication. In cases of overdose, symptoms such as confusion, drowsiness, or seizures may appear, necessitating immediate medical attention.

Serious side effects

• Hives
• severe swelling (edema)
• facial swelling
• angioedema
• chest tightness
• difficulty breathing
• severe respiratory depression
• cold sweats
• pallor
• severe rash with fever

Mild side effects

• Dizziness
• drowsiness
• headache
• confusion
• lethargy
• constipation
• indigestion
• nausea
• dry mouth
• vomiting

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy over time.

Appearance

White to pale yellow oblong film-coated extended-release tablets

Package unit

30 tablets (6 tablets/PTP x 5)