Ogosillin Tablet 625 mg (Amoxicillin and Clavulanate Potassium)

Adult dose

Adults and children aged 12 years or older or weighing 40 kg or more: Amoxicillin/Clavulanate Potassium, 250 mg/125 mg per dose, orally three times a day every 8 hours, and in severe cases and respiratory infections, the dose may be escalated to 500 mg/125 mg per dose. In cases of renal impairment, dosage should be adjusted based on creatinine clearance. - Creatinine clearance 10-30 mL/min: 250 mg/125 mg Amoxicillin/Clavulanate Potassium every 12 hours.

Child dose

In children weighing less than 40 kg: administer by reducing the dosage according to the adult method.

This medicine should not be used in patients who have hypersensitivity to certain ingredients or are allergic to beta-lactam drugs. Particularly, patients with infectious mononucleosis or lymphocytic leukemia should be cautious due to the risk of rash. Patients with a history of liver function problems should be careful as taking this medicine may worsen liver function. Patients with moderate or severe renal impairment may have increased drug concentration and need to adjust the dosing interval. Patients with an allergic constitution or a history of symptoms such as bronchial asthma, rash, or hives should use this medicine with caution. Patients who find oral intake difficult, the elderly, or those in poor general condition should be careful due to the risk of bleeding from vitamin K deficiency. In cases of gastrointestinal diseases such as vomiting or diarrhea, proper absorption of the drug may not occur. If diarrhea, abdominal pain, or blood in the stool occurs during use, stop taking the medicine immediately and seek medical advice. Symptoms of liver function abnormality may occur during or after treatment, so liver function tests are necessary for long-term use. If hypersensitivity reactions such as skin rash, itching, or difficulty breathing occur, stop taking the medication immediately and follow a doctor's instructions. Blood tests may show decreased blood cell count or bleeding tendency, so report any unusual symptoms to the hospital. Pregnant or breastfeeding women should consult a doctor before taking this medication, and especially in early pregnancy, it is advisable to avoid use. In children, it is recommended only for those aged 12 years or more or weighing 40 kg or more, as there is limited experience in younger age groups, requiring caution. Elderly patients may experience side effects more easily due to decreased physical function, so dosage and administration intervals should be adjusted while observing them. There may be interactions with other medications, so inform the healthcare provider of any drugs currently being taken. In cases of overdose, gastrointestinal symptoms, renal problems, and rarely neurological abnormalities may occur, necessitating immediate emergency treatment. This medicine should be stored in a special container that is dry and airtight below 25 degrees Celsius, and the duration and dosage should be strictly followed to minimize the occurrence of side effects.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reaction
• Severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe dermatological reactions
• Shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever and respiratory abnormalities
• Jaundice, severe lethargy, liver abnormalities (jaundice)
• Sudden and severe headaches, thunderclap headache,

Mild side effects

Diarrhea, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, hyperacidity, loose stools, dry mouth, acute pancreatitis, candidiasis, antibiotic-associated colitis, membranous colitis, blood in the stool, itching, erythema multiforme, skin rash, symptoms of serum sickness (fever, joint pain, lymphadenopathy, etc.), reversible leukopenia, thrombocytopenia, anemia, thrombocytopenic purpura, eosinophilia

This medicine is kept in a special container that is airtight and moisture-proof. When storing, it is advisable to place it in a cool place between 1 and 25 degrees Celsius. This helps maintain the drug's effectiveness for a longer period.

Appearance

This medicine is a white or almost white oval film-coated tablet.

Package unit

40 tablets (4 tablets/PTP*10)