Medication info
Lyribea Capsule 50 mg (Pregabalin)

Lyribea Capsule 50 mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›50mg / 1 capsule
Manufacturer / importer
대웅바이오(주)
Appearance
Hard capsules with white upper and lower parts containing a white to pale yellow powder
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201805040 · Approved 2018.12.12 · Insurance code 694002040

Summary

Main use
Improvement of neuropathic pain, epilepsy (partial seizures), and fibromyalgia
Who takes it
Adults · Children
Adult dose
This medication is administered orally in two divided doses regardless of meals. 1. Neuropathic pain - Peripheral neuropathic pain: Initial dose of 150 mg/day; may increase to 300 mg/day after 3 to 7 days, and up to a maximum of 600 mg/day in intervals of 7 days if necessary. - Central neuropathic pain: Initial dose of 150 mg/day, may increase to 300 mg/day after 1 week.
Child dose
Administration is not recommended for children under 12 years of age and adolescents aged 12-17 due to insufficient safety and efficacy data.

Ingredients

Manufacturer
대웅바이오(주)

Efficacy & effects

Improvement of neuropathic pain, epilepsy (partial seizures), and fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used to treat neuropathic pain in adults involving peripheral and central nervous systems. It is also effective as an adjunctive treatment for partial seizures in patients with epilepsy. Additionally, it helps alleviate symptoms of fibromyalgia. In summary, it is used for the treatment of neuropathic pain, partial seizures in epilepsy, and fibromyalgia.

How to take

Adult dose

This medication is administered orally in two divided doses regardless of meals. 1. Neuropathic pain - Peripheral neuropathic pain: Initial dose of 150 mg/day; may increase to 300 mg/day after 3 to 7 days, and up to a maximum of 600 mg/day in intervals of 7 days if necessary. - Central neuropathic pain: Initial dose of 150 mg/day, may increase to 300 mg/day after 1 week.

Child dose

Administration is not recommended for children under 12 years of age and adolescents aged 12-17 due to insufficient safety and efficacy data.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so you must consult a physician immediately if you experience symptoms of depression or mood changes while taking it. It should not be used if there is a hypersensitivity reaction to this medication. Diabetic patients should be cautious as weight gain may require adjustments to blood sugar control medications. In case of serious allergic reactions such as angioedema, the medication should be stopped immediately. Elderly individuals may be prone to side effects such as dizziness or drowsiness, so caution is advised until they become accustomed to the medication. Vision blurriness or changes in eyesight may occur, and if these symptoms occur, notify a healthcare provider. When discontinuing this medication, withdrawal symptoms such as insomnia, headache, and anxiety may occur; therefore, it should be stopped gradually in consultation with a healthcare professional. Patients with a history of substance abuse may be at a higher risk of misuse, and special caution is required when taking this medication. Patients with reduced kidney function may need dose adjustments. Patients with heart conditions should use this medication cautiously due to the risk of congestive heart failure. Co-administration with opioid analgesics can increase central nervous system depression, so caution is warranted. Individuals with respiratory or neurological diseases, as well as the elderly, are at higher risk of severe respiratory depression, so consultation with a physician is necessary prior to use. During early pregnancy, there is a risk of congenital malformations; thus, women who are pregnant or planning to become pregnant must consult a physician. Breastfeeding women should consult a healthcare provider regarding the potential transmission of this medication into breast milk and its effects on the infant. Caution is advised as dizziness and drowsiness can increase the risk of accidents during driving or operating machinery. Severe allergic skin reactions may occur, so if any abnormal symptoms such as rash or swelling develop, stop taking it immediately and notify a healthcare provider. In case of overdose, symptoms such as confusion, drowsiness, and convulsions may occur, and immediate medical attention is necessary if overdose is suspected.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (including angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain on the mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, markedly decreased urine output, generalized swelling with elevated blood pressure, neutropenia

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • loss of coordination
  • irritability
  • depression
  • euphoria
  • reduced libido
  • insomnia
  • depersonalization
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  • altered sexual sensation
  • restlessness
  • anxiety
  • mood swings
  • emotional blunting
  • emotional elevation
  • difficulty in finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • numbness
  • ataxia
  • motor coordination difficulties
  • balance disorders
  • amnesia
  • attention deficit
  • memory impairment
  • tremors
  • speech disorders
  • sensory disturbances
  • decreased sensation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. The recommended storage temperature is between 15 to 30 degrees Celsius.

Appearance and packaging

Appearance

Hard capsules with white upper and lower parts containing a white to pale yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.