Augment Duo Syrup (Amoxicillin·Clavulanate Potassium (7:1))

Adult dosage

For recurrent tonsillitis and other upper respiratory infections, lower respiratory infections, urinary tract infections, and moderate to severe skin and soft tissue infections, take 25 mg/3.6 mg of amoxicillin/clavulanate potassium per kg of body weight, divided into two doses daily. In the case of moderate infections such as otitis media, sinusitis, and lower respiratory infections such as bronchopneumonia, and urinary tract infections, 45 mg/6.4 mg of amoxicillin/clavulanate potassium per kg of body weight is recommended.

Children's dosage

The 7:1 syrup is unsuitable for children under 2 months old. The 7:1 syrup is not suitable for pediatric patients with renal failure.

This drug contains the artificial sweetener aspartame, and should not be used by patients with phenylketonuria, a hereditary condition. The daily intake of aspartame should be limited to below the WHO recommended level, and the smallest amount possible should be used for safety. Patients who have had allergic reactions to this drug or beta-lactam antibiotics should not be administered this medication, and those with infectious mononucleosis or lymphocytic leukemia should also avoid it due to the risk of rashes. Patients with a history of jaundice or liver dysfunction due to this drug or penicillin are prohibited from taking it. Patients with poor liver function or moderate to severe renal impairment should use it cautiously, and those who are allergic or elderly, as well as patients receiving parenteral nutrition, need special attention. Patients with gastrointestinal diseases such as vomiting or diarrhea may not absorb the medication properly, so caution is necessary. During treatment, gastrointestinal symptoms such as diarrhea, abdominal pain, and vomiting may occur, and in severe cases, discontinuation of the medication and consultation with a physician is required. Since liver function may elevate, hepatitis and jaundice symptoms can appear, long-term use requires liver function tests. Severe skin reactions such as rashes, hives, or in severe cases, Stevens-Johnson syndrome may occur, so if abnormal symptoms arise, administration should be stopped immediately. Blood tests have rarely reported blood abnormalities such as leukopenia and anemia; inform healthcare personnel if abnormal symptoms occur. Central nervous system side effects such as anxiety, confusion, and seizures may occur, so caution is needed. Regular checks are required as kidney function may decline, and medication should be stopped if abnormalities are found. This drug may interact with other medications, so inform healthcare providers of any medications currently being taken. Particular caution is needed when used with anticoagulants, anti-inflammatory medications, and oral contraceptives. It should be avoided during the first three months of pregnancy, and women who are pregnant or breastfeeding should use it cautiously after consulting a doctor. It is not recommended for use in premature infants and neonates, as safety has not been established. Elderly patients may experience adverse reactions more easily due to decreased kidney and liver function, therefore dosing and intervals should be adjusted and monitored. In case of overdose, gastrointestinal symptoms and neurological abnormalities may occur, so inform healthcare personnel immediately and receive appropriate treatment. After mixing, refrigerate and use within 7 days, paying attention to temperature and humidity during storage. The use of this drug should only be for the necessary minimum duration after sensitivity testing to help prevent resistant strains from occurring. If any adverse symptoms appear during treatment, it is important to consult healthcare personnel immediately to take appropriate measures.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, significantly reduced urine output, severe swelling throughout the body and increased blood pressure, anaphylaxis, shock

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This drug should be stored in a tightly sealed container to protect it from air and humidity, and it is recommended to store it in a cool, dry place below 25 degrees Celsius. This helps maintain the effectiveness of the medication for a longer period.

Appearance

A whitish powder with a distinctive smell, used as a syrup that is dissolved before use.

Package unit

50mL/bottle, 500mL/bottle