Medication info
Wontraset Semi Tablet

Wontraset Semi Tablet

Prescription medicationTablet경구
Ingredient · strength
Tramadol Hydrochloride›18.75mg / 1 tabletAcetaminophen›162.5mg / 1 tablet
Manufacturer / importer
엔비케이제약(주)
Appearance
Pale yellow oblong film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201804529 · Approved 2018.11.15 · Insurance code 054800230

Summary

Main use
Relief of moderate to severe acute and chronic pain
Who takes it
Adults · Children
Adult dose
Children and adults aged 12 years and over: The dosage should be adjusted based on the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and the subsequent dosing interval should be at least 6 hours apart, but should not exceed 16 tablets in one day. Administer the lowest effective dose for the shortest period possible. Do not use this medication for longer than necessary, and if prolonged treatment is needed due to the nature and severity of the condition, regular monitoring should be conducted to determine if continued use of this medication is warranted. In elderly patients, administer the usual adult dose. However, for patients over 75 years old, the elimination half-life of tramadol when taken orally is increased by 17%, so they should take this medication at intervals of at least 6 hours. In patients with renal impairment, for moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. For severe renal impairment (creatinine clearance less than 10 mL/min), it is not recommended to administer this medication. Tramadol is removed very slowly during hemodialysis and filtration, so there is no need to re-dose this medication after dialysis to maintain analgesic effect. In patients with hepatic impairment, careful consideration should be given to extending the dosing interval for those with moderate hepatic impairment. It is not recommended to administer this medication to patients with severe hepatic impairment.
Child dose
Children and adults aged 12 years and over: The dosage should be adjusted based on the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and the subsequent dosing interval should be at least 6 hours apart, but should not exceed 16 tablets in one day.

Ingredients

Manufacturer
엔비케이제약(주)

Efficacy & effects

Relief of moderate to severe acute and chronic pain

  • Moderate to severe acute and chronic pain
View approved original text

This medication is used to relieve acute and chronic pain ranging from moderate to severe.

How to take

Adult dose

Children and adults aged 12 years and over: The dosage should be adjusted based on the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and the subsequent dosing interval should be at least 6 hours apart, but should not exceed 16 tablets in one day. Administer the lowest effective dose for the shortest period possible. Do not use this medication for longer than necessary, and if prolonged treatment is needed due to the nature and severity of the condition, regular monitoring should be conducted to determine if continued use of this medication is warranted. In elderly patients, administer the usual adult dose. However, for patients over 75 years old, the elimination half-life of tramadol when taken orally is increased by 17%, so they should take this medication at intervals of at least 6 hours. In patients with renal impairment, for moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. For severe renal impairment (creatinine clearance less than 10 mL/min), it is not recommended to administer this medication. Tramadol is removed very slowly during hemodialysis and filtration, so there is no need to re-dose this medication after dialysis to maintain analgesic effect. In patients with hepatic impairment, careful consideration should be given to extending the dosing interval for those with moderate hepatic impairment. It is not recommended to administer this medication to patients with severe hepatic impairment.

Child dose

Children and adults aged 12 years and over: The dosage should be adjusted based on the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and the subsequent dosing interval should be at least 6 hours apart, but should not exceed 16 tablets in one day.

Precautions

This medication may strain the liver, so individuals who regularly consume a lot of alcohol should consult their doctor or pharmacist before taking it. This medication can rarely cause serious skin reactions, so if a rash or allergic symptoms occur, you should stop taking it immediately and consult a healthcare provider. The tramadol component included in this medication may trigger seizures, so individuals with a history of seizures or a high risk of seizures should take it cautiously, and the risk of seizures may increase when taken with certain medications. This medication can rarely cause serious allergic reactions; therefore, individuals who have had allergic reactions in the past should not take it. Patients with severe respiratory diseases may have difficulty breathing while taking this medication, so it should be taken under the supervision of healthcare professionals. Taking this medication with alcohol or other central nervous system depressants can result in serious drowsiness or respiratory suppression, so combination should be avoided or taken with great caution. Patients with head injuries or brain diseases should be careful as taking this medication may increase intracranial pressure or worsen symptoms. This medication can lead to physical and psychological dependence; thus, careful monitoring for signs of dependence is necessary during use. Patients with impaired liver function must consult their doctor before taking this medication, as excessive dosing can cause liver damage. Individuals with certain genetic metabolic characteristics have a higher risk of side effects from this medication, and special management by a physician is required in such cases. This medication should not be administered to children under 12 years old or adolescents under 18 after certain surgeries due to the high risk of respiratory suppression. Patients with sleep apnea or hypoxemia should continuously monitor for worsening symptoms while taking this medication. Elderly patients or those in poor physical condition should exercise additional caution when taking this medication, and should consult with healthcare providers immediately if unusual symptoms arise. Women who are pregnant or may become pregnant should carefully consider the potential effects on the fetus when taking this medication, and nursing mothers should avoid using it. This medication can cause drowsiness or dizziness, so caution is needed when driving or operating machinery. In cases of overdose, serious respiratory suppression, seizures, and liver damage may occur, so it is important to adhere to the prescribed dosage and seek immediate medical attention in emergencies. This medication may interact with other analgesics or medications; therefore, if you are taking other medications, you must inform your healthcare provider. This medication should be kept in a secure location out of the reach of children to prevent misuse or accidents.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (skin or eyes turning yellow), extreme drowsiness, sudden and very severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urinary issues

Mild side effects

  • Decreased appetite
  • insomnia
  • depression
  • dizziness
  • headache
  • drowsiness
  • nausea
  • vomiting
  • constipation
  • dry mouth
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  • diarrhea
  • indigestion
  • abdominal pain
  • abdominal discomfort
  • flatulence
  • pruritus
  • sweating
  • rash
  • fatigue
  • flushing
  • anxiety
  • irritability
  • emotional instability
  • euphoria
  • decreased libido
  • sleep disorders
  • confusion
  • disorientation
  • excitement
  • abnormal dreams
  • drug abuse
  • hallucinations
  • withdrawal syndrome
  • migraine
  • lethargy
  • sensory loss
  • tremor
  • paresthesia
  • attention deficit

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is best to keep the medication at a temperature between 1 and 30 degrees Celsius. This way of storing helps to maintain the efficacy of the medication for a longer period.

Appearance and packaging

Appearance

Pale yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.