Viewing nowCombinationWontraset Semi Tablet
Tramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
NBK Pharmaceutical Co., Ltd.

MFDS item code 201804529 · Approved 2018.11.15 · Insurance code 054800230
Relief of moderate to severe acute and chronic pain
This medication is used to relieve acute and chronic pain ranging from moderate to severe.
Children and adults aged 12 years and over: The dosage should be adjusted based on the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and the subsequent dosing interval should be at least 6 hours apart, but should not exceed 16 tablets in one day. Administer the lowest effective dose for the shortest period possible. Do not use this medication for longer than necessary, and if prolonged treatment is needed due to the nature and severity of the condition, regular monitoring should be conducted to determine if continued use of this medication is warranted. In elderly patients, administer the usual adult dose. However, for patients over 75 years old, the elimination half-life of tramadol when taken orally is increased by 17%, so they should take this medication at intervals of at least 6 hours. In patients with renal impairment, for moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. For severe renal impairment (creatinine clearance less than 10 mL/min), it is not recommended to administer this medication. Tramadol is removed very slowly during hemodialysis and filtration, so there is no need to re-dose this medication after dialysis to maintain analgesic effect. In patients with hepatic impairment, careful consideration should be given to extending the dosing interval for those with moderate hepatic impairment. It is not recommended to administer this medication to patients with severe hepatic impairment.
Children and adults aged 12 years and over: The dosage should be adjusted based on the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and the subsequent dosing interval should be at least 6 hours apart, but should not exceed 16 tablets in one day.
This medication may strain the liver, so individuals who regularly consume a lot of alcohol should consult their doctor or pharmacist before taking it. This medication can rarely cause serious skin reactions, so if a rash or allergic symptoms occur, you should stop taking it immediately and consult a healthcare provider. The tramadol component included in this medication may trigger seizures, so individuals with a history of seizures or a high risk of seizures should take it cautiously, and the risk of seizures may increase when taken with certain medications. This medication can rarely cause serious allergic reactions; therefore, individuals who have had allergic reactions in the past should not take it. Patients with severe respiratory diseases may have difficulty breathing while taking this medication, so it should be taken under the supervision of healthcare professionals. Taking this medication with alcohol or other central nervous system depressants can result in serious drowsiness or respiratory suppression, so combination should be avoided or taken with great caution. Patients with head injuries or brain diseases should be careful as taking this medication may increase intracranial pressure or worsen symptoms. This medication can lead to physical and psychological dependence; thus, careful monitoring for signs of dependence is necessary during use. Patients with impaired liver function must consult their doctor before taking this medication, as excessive dosing can cause liver damage. Individuals with certain genetic metabolic characteristics have a higher risk of side effects from this medication, and special management by a physician is required in such cases. This medication should not be administered to children under 12 years old or adolescents under 18 after certain surgeries due to the high risk of respiratory suppression. Patients with sleep apnea or hypoxemia should continuously monitor for worsening symptoms while taking this medication. Elderly patients or those in poor physical condition should exercise additional caution when taking this medication, and should consult with healthcare providers immediately if unusual symptoms arise. Women who are pregnant or may become pregnant should carefully consider the potential effects on the fetus when taking this medication, and nursing mothers should avoid using it. This medication can cause drowsiness or dizziness, so caution is needed when driving or operating machinery. In cases of overdose, serious respiratory suppression, seizures, and liver damage may occur, so it is important to adhere to the prescribed dosage and seek immediate medical attention in emergencies. This medication may interact with other analgesics or medications; therefore, if you are taking other medications, you must inform your healthcare provider. This medication should be kept in a secure location out of the reach of children to prevent misuse or accidents.
Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (skin or eyes turning yellow), extreme drowsiness, sudden and very severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urinary issues
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is best to keep the medication at a temperature between 1 and 30 degrees Celsius. This way of storing helps to maintain the efficacy of the medication for a longer period.
Pale yellow oblong film-coated tablet
30 tablets/bottle, 300 tablets/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Viewing nowCombinationTramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
NBK Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Yuyoung Pharmaceutical Co., Ltd.
CombinationAcetaminophen 325mg · Tramadol Hydrochloride 37.5mg
Tablet · Prescription medication · Combination
Youyoung Pharmaceutical Co., Ltd.
CombinationTramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
Korea Pharmaceutical Co., Ltd.
CombinationTramadol Hydrochloride 37.5mg · Acetaminophen 325mg
Tablet · Prescription medication · Combination
Korea United Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Shinpoong Pharmaceutical Co., Ltd.
CombinationAcetaminophen 325mg · Tramadol Hydrochloride 37.5mg
Tablet · Prescription medication · Combination
Sinphong Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Albozen Korea Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.