Medication info

Parakei Injection (Acetaminophen)

Prescription medicationInjections
Ingredient · strength
Acetaminophen›1g / 100mL
Manufacturer / importer
주식회사제뉴원사이언스
Appearance
A clear, light yellow transparent liquid filled in a colorless and transparent parenteral plastic container.
Packaging
75ml/bag, 100ml/bag
Approval status
Active

MFDS item code 201804294 · Notified 2018.10.30

Summary

Main use
Rapid relief treatment for moderate pain (post-surgery) and fever.
Who uses it
Adults · Children
Adult dosage
For adults weighing 50 kg or more, administer acetaminophen as 1000 mg, four times a day, with a minimum interval of about 4 hours. The maximum daily dose should not exceed 4 grams. For children over 33 kg and adults who weigh less than 50 kg, administer approximately 15 mg/kg (equivalent to 1.5 ml/kg) of acetaminophen for a single dose, with a minimum interval of 4 hours. The maximum daily dose should not exceed 60 mg/kg or 4 grams.
Children's dosage
For children weighing 33 kg (approximately 11 years old) or more, administer acetaminophen at about 15 mg/kg for a single dose, with a minimum interval of 4 hours. The maximum dosage per day is 60 mg/kg or 4 grams.

Ingredients

Manufacturer
주식회사제뉴원사이언스

Efficacy & effects

Rapid relief treatment for moderate pain (post-surgery) and fever.

  • Pain
  • high fever
  • moderate pain
  • fever
View approved original text

This medication is used when pain or high fever needs to be administered quickly via intravenous injection or when other routes of administration are difficult. It is particularly effective in alleviating moderate pain occurring after surgery for a short period and in reducing fever temporarily. In other words, it is primarily used for the treatment of postoperative pain and high fever.

Dosage and Administration

Adult dosage

For adults weighing 50 kg or more, administer acetaminophen as 1000 mg, four times a day, with a minimum interval of about 4 hours. The maximum daily dose should not exceed 4 grams. For children over 33 kg and adults who weigh less than 50 kg, administer approximately 15 mg/kg (equivalent to 1.5 ml/kg) of acetaminophen for a single dose, with a minimum interval of 4 hours. The maximum daily dose should not exceed 60 mg/kg or 4 grams.

Children's dosage

For children weighing 33 kg (approximately 11 years old) or more, administer acetaminophen at about 15 mg/kg for a single dose, with a minimum interval of 4 hours. The maximum dosage per day is 60 mg/kg or 4 grams.

Precautions

This medication must be administered with precise dosage measurements. Serious side effects can occur due to confusion between milligrams and milliliters. Once oral medication can be taken, it is advisable to use appropriate analgesics immediately. Be sure to check if other acetaminophen-containing medications are being taken to avoid overdosing. Exceeding the recommended dosage may severely damage the liver, so it is crucial to adhere strictly to the dosage instructions. Symptoms of liver damage usually appear between 2 to 6 days after administration, so if any unusual symptoms appear, immediate medical attention is necessary. Patients with poor liver function or those who regularly consume alcohol should consult a doctor before taking this medication. This medication can rarely cause serious skin reactions; if a skin rash or allergic symptoms appear, it should be stopped immediately. Patients allergic to acetaminophen or this medication, those with peptic ulcers, severe liver or kidney disease, or severe heart failure should not use this medication. Additionally, patients with a history of aspirin-induced asthma or those taking specific medications should avoid this drug. Elderly patients, pregnant women, and breastfeeding mothers should use this medication cautiously and consult a doctor if necessary. This medication can interact with other drugs that may increase hepatotoxicity, so be sure to inform your healthcare provider of any medications being taken. Overdose may present with symptoms like nausea, vomiting, loss of appetite, and abdominal pain, and in severe cases, can lead to liver damage and be life-threatening, requiring immediate hospital care. The use of this medication during pregnancy is relatively safe, but must be taken according to a doctor's instructions. While small amounts may be excreted in breast milk during breastfeeding, no reports of specific adverse reactions have been noted, but caution is warranted. This medication should be stored in a cool place at temperatures below 30 degrees Celsius, and should not be refrigerated or frozen. After opening, it should be checked for discoloration or foreign substances and should only be used for a single dosage.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), anaphylactic shock, shock, acute generalized exanthematous pustulosis, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute renal failure, thrombocytopenia, fulminant hepatitis, liver necrosis, liver failure, angioedema, anaphylaxis, severe allergic reactions, liver abnormalities (jaundice).

Mild side effects

  • Fatigue
  • low blood pressure
  • elevated liver transaminase levels
  • agranulocytosis
  • neutropenia
  • leukopenia
  • thrombocytopenia
  • neurological disorders
  • maculopapular rash
  • injection site reactions
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  • papulovesicular rash
  • drug-induced pemphigus-like reactions
  • pustular rashes
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • tachycardia
  • nausea
  • vomiting
  • erythema
  • flushing
  • itching
  • rash
  • high anion gap metabolic acidosis
  • malaise
  • constipation
  • sputum production
  • sensory disturbances
  • dizziness
  • decrease in hemoglobin
  • and urinary disorders.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored at room temperature between 1 and 30 degrees Celsius, and it is important to keep it in a well-sealed container to prevent air or moisture from entering.

Appearance and packaging

Appearance

A clear, light yellow transparent liquid filled in a colorless and transparent parenteral plastic container.

Package unit

75ml/bag, 100ml/bag

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.