Aiklan Tablet 375mg (Amoxicillin-Potassium Clavulanate)

Adult dose

Adults and children over 12 years old or weighing 40 kg or more should take 250 mg/125 mg of amoxicillin/potassium clavulanate orally three times a day at 8-hour intervals. In cases of severe and respiratory infections, the dose may be increased to 500 mg/125 mg once. For patients with kidney impairment, the dose should be adjusted according to creatinine clearance. - For creatinine clearance greater than 30 mL/min: dosage adjustment is not necessary.

Child dose

Children under 12 years old or weighing less than 40 kg should be administered a reduced dose using the same method.

This medication is a penicillin class antibiotic used for the treatment of bacterial infections. It should not be administered to patients with hypersensitivity to beta-lactam antibiotics or those who have previously experienced severe allergic reactions. Particularly, caution is necessary for patients with infectious mononucleosis or lymphoblastic leukemia due to the higher risk of adverse reactions such as rash. Patients with a history of liver dysfunction or jaundice should consult their doctor before using this medication. For patients with compromised liver or kidney function, the concentration of this medication may increase, so dosage and administration intervals should be adjusted carefully. Patients who are allergic, elderly, or have gastrointestinal diseases should also be cautious as the likelihood of side effects may be higher. This medication can cause gastrointestinal side effects such as diarrhea, nausea, vomiting, and abdominal pain, and in severe cases, serious intestinal conditions like pseudomembranous colitis may occur. If these symptoms appear, use should be stopped immediately, and medical attention should be sought. Liver enzyme levels may rise or jaundice symptoms may appear, especially reported more frequently in men over 60 years old. Long-term use of this medication for more than 14 days increases the risk of liver dysfunction, necessitating regular check-ups. Rarely, allergic reactions such as itching, skin rash, severe dermatitis, serum sickness symptoms, angioedema, reversible leukopenia, thrombocytopenia, hemolytic anemia, anemia, thrombocytopenic purpura, eosinophilia, leukemia may occur; should these symptoms arise, medication use should be stopped immediately and directives from a physician should be followed. Central nervous system side effects may occur rarely, including anxiety, confusion, drowsiness, and seizures, and caution is required in patients with diminished kidney function or when administered in high doses. Pregnant or breastfeeding women should carefully consider the impact of using this medication on the fetus or infant and are particularly advised to avoid it during the first three months of pregnancy. This medication may interact with other drugs, particularly anticoagulants, anti-inflammatories, and other antibiotics, so it is important to inform healthcare professionals of any concurrent medications. In cases of overdose, gastrointestinal symptoms, electrolyte imbalances, and rarely kidney failure or seizures may occur, necessitating immediate treatment at a medical facility. Store in a sealed container to prevent moisture and keep in a cool place between 1 to 25 degrees Celsius. This will help maintain its efficacy for a longer period.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, anaphylaxis, anaphylactic shock, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, blistering dermatitis), severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, respiratory issues (bronchospasm, laryngeal edema, dyspnea), yellowing of skin or eyes (cholestatic jaundice),

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This medication is stored in a sealed container to prevent moisture, and should be kept in a cool place between 1 to 25 degrees Celsius. This storage method helps maintain the efficacy of the medication for a longer time.

Appearance

White or almost white oval film-coated tablets.

Package unit

100 tablets (10 tablets/PTP X 10)