Bibozon Coolsan

Adult dose

For adults aged 18 and older, a total of 2L of the prepared solution is taken, 1L the evening before and 1L the next morning before the colonoscopy. 1) Split dosing method: Take 1L of the prepared solution in the evening before the examination over 1 hour (250mL every 15 minutes), followed by an additional 500mL of water. Repeat the same method for 1L of the prepared solution in the morning and drink another 500mL of water. This process must be completed at least 1 hour before starting the colonoscopy.

This drug can rarely cause generalized tonic-clonic seizures even in patients without a seizure history, so caution is particularly needed in patients at risk of electrolyte imbalances. Patients taking diuretics or ACE inhibitors that can cause electrolyte imbalances or those suspected of hyponatremia should use this drug carefully. This medication should not be administered to patients with bowel obstruction, gastrointestinal obstruction, perforation, toxic colitis, or toxic megacolon, and it should be used cautiously in patients with severe ulcerative colitis. Patients with allergies to this drug or its components, those suspected of gastrointestinal obstruction or perforation, dehydrated patients, those with severe heart failure, or active cancer patients should not use this medication. Safety and efficacy have not been established in children under 18 years old, so it should not be administered. Patients with intestinal stenosis or severe constipation, elderly patients, frail patients, those with a vomiting reflex disorder, or patients with altered consciousness should use this drug with increased caution. This medication may cause various adverse reactions such as hunger, hypophosphatemia, hypokalemia, sleep disturbances, dizziness, headache, upper abdominal pain, abdominal pain, nausea, abdominal distension, anal discomfort, vomiting, dyspepsia, difficulty swallowing, lethargy, thirst, tremors, discomfort, decreased blood bicarbonate, decreased blood calcium, hypercalcemia, decreased or increased blood chloride, increased blood phosphate, liver function abnormalities, rash, runny nose, dermatitis, fever, chills, tremors, and renal function impairment. In particular, major side effects such as gastric mucosal damage, serious gastrointestinal bleeding, and acute pulmonary edema have been reported in elderly patients over 60 years old, requiring heightened caution. Before and during administration of this medication, the patient's bowel movement status should be verified to observe for proper bowel activity, and in cases of severe abdominal distension or pain, the rate of administration should be adjusted or discontinued, and a physician should be consulted. If symptoms of fluid and electrolyte imbalance appear, blood tests should be conducted to verify the status and appropriate treatment should be provided. It is important for patients with heart disease or at risk of electrolyte imbalances to check their condition with ECGs and blood tests before and after administration. This medication may cause diarrhea, so adequate hydration before and after administration is necessary. When used in conjunction with irritating laxatives, the risk of ulceration or ischemic colitis in the intestinal mucosa increases, so it is advisable not to use them together. This medication should be taken at least 1 hour after finishing a meal, and solid foods should be avoided during administration. Bowel movements typically begin about 1 hour after taking this medication, and abdominal distension may occur beforehand. The absorption of other oral medications may be hindered when this medication is taken, so it is advisable to space the administration times apart. Pregnant or breastfeeding women should only use this medication when the need for diagnosis is clearly established, as its safety has not been determined. In case of overdose, dehydration and electrolyte disturbances can become severe, and patients who have overdosed require immediate observation and treatment by medical personnel. This medication should be taken immediately after preparation, and any solution not used within 24 hours should be discarded, keeping it out of reach of children. Furthermore, transferring the solution to another container is not advisable for quality maintenance.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, anaphylaxis, upper gastrointestinal bleeding due to Mallory-Weiss tear, esophageal perforation, cardiac arrest, acute pulmonary edema, respiratory distress, chest tension, lip swelling, tongue swelling, facial swelling, respiratory problems, severe swelling or urinary abnormalities, severe allergic reactions, severe skin adverse reactions, severe neurological symptoms, liver abnormalities (jaundice)

Mild side effects

• Hunger
• hypophosphatemia
• hypokalemia
• sleep disturbances
• dizziness
• headache
• upper abdominal pain
• abdominal pain
• nausea
• abdominal distension

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It should also be kept away from extreme heat or cold, ideally at room temperature between 1 to 30 degrees Celsius.

Appearance

A preparation: A white or slightly yellow powder in an aluminum foil pouch with a lemon scent. B preparation: White to slightly yellow crystals or crystalline powder in an aluminum foil pouch with no smell and a sour taste.

Package unit

1 box (A preparation 4 pouches + B preparation 4 pouches)