Terachamps Tablet 1 mg (Varenicline Salicylate)

Adult dosage

After dose titration over 1 week, administer 1 mg twice daily. Days 1 – 3: 0.5 mg once daily Days 4 – 7: 0.5 mg twice daily Day 8 – end of treatment: 1 mg twice daily This medicine should be taken after meals with plenty of water. Patients who cannot tolerate the adverse reactions of Zeropix may temporarily or permanently reduce the dose. Zeropix is administered for 12 weeks. For patients who successfully quit smoking with the first 12 weeks of treatment, an additional 12 weeks of Zeropix is recommended to increase the likelihood of long-term abstinence. For patients who cannot or do not wish to stop smoking abruptly, consider gradually reducing smoking while taking this medicine. Within the first 4 weeks after starting this medicine, reduce smoking by 50% compared with before treatment; reduce it by a further 50% within the following 4 weeks, and continue to reduce smoking so that complete abstinence is achieved by week 12. Administer this medicine for an additional 12 weeks for a total treatment duration of 24 weeks. No dose adjustment is necessary in patients with mild (estimated creatinine clearance > 50 mL/min and ≤ 80 mL/min) to moderate (estimated creatinine clearance ≥ 30 mL/min and ≤ 50 mL/min) renal impairment. In patients with severe renal impairment (estimated creatinine clearance < 30 mL/min), the recommended starting dose of Zeropix is 0.5 mg once daily. If needed, the maximum dose is 0.5 mg twice daily. In patients with end-stage renal disease receiving hemodialysis, a maximum dose of 0.5 mg once daily may be administered if well tolerated. No dose adjustment is necessary in patients with hepatic impairment. Because renal function is more likely to be reduced in elderly patients, use caution when selecting the dose; monitoring renal function may be useful.

Children's dosage

Use in patients under 18 years of age is not recommended.

This medication is used to help with smoking cessation. Care should be taken regarding mental health while taking this medication, as serious psychiatric symptoms such as depression, anxiety, and suicidal thoughts or behaviors may occur. If such symptoms arise, discontinue use immediately and consult a physician. This medication should not be administered to patients with hypersensitivity, and women who are pregnant or breastfeeding should use it cautiously. Breastfeeding women should consult with their doctor on whether to take this medication as it may pass into breast milk. During the initial phase of treatment, nausea, headache, insomnia, and unusual dreams may commonly occur, mostly ranging from mild to moderate severity. Nausea is particularly a common side effect and can be alleviated through initial dosage adjustments. While taking this medication, individuals should be cautious when engaging in activities that require alertness, such as driving or operating machinery, as symptoms like drowsiness or dizziness may occur. Patients with cardiovascular disease should consult a physician before taking this medication, and if heart-related symptoms worsen, they should inform healthcare personnel immediately. Moreover, this medication generally has a low potential for interactions with other drugs, but alcohol consumption may increase side effects, so it is advisable to avoid alcohol during treatment. In the event of an overdose, visit a medical facility immediately for appropriate care, and keep the medication out of reach of children. It is important to store the medication in its original container to maintain its quality.

• Suicidal ideation
• suicidal behavior
• suicide
• changes in behavior or thoughts
• depression
• mania
• mood changes
• psychosis
• aggressive behavior
• hallucinations

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is safe to store at room temperature between 1°C and 30°C.

Appearance

Light blue, double convex, rectangular film-coated tablet

Package unit

28 tablets (14 tablets/Blister X2)