Cefaclor Capsule 250 mg (Cefaclor Hydrate)

Adult dose

As Cefaclor hydrate, take 250 mg orally every 8 hours. In cases of severe infections (such as pneumonia) and infections with low susceptibility, the dose can be doubled. For acute gonococcal urethritis, administer this drug 3g combined with 1g of probenecid in a single dose.

Child dose

Administer 20 mg per kg of body weight divided every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, 40 mg per kg of body weight can be administered, with a maximum dose of

This drug acts by binding to particular proteins and inhibiting bacterial cell wall synthesis, thus killing the bacteria. Before using this drug, it should not be used if there has been a history of severe allergic reactions or shock from this drug or similar classes of antibiotics. It should be used with caution in patients allergic to penicillin antibiotics or with a history of asthma, rashes, or allergies. Patients with severely impaired kidney function, elderly patients, patients with poor nutritional status, or those with a history of gastrointestinal diseases should also use this drug with caution. Rarely, shock, severe allergic reactions, severe skin rashes, or skin necrosis may occur, and if symptoms appear, medication should be stopped immediately, and medical treatment should be sought. Blood tests may show abnormalities such as leukopenia, anemia, and thrombocytopenia, so regular testing is necessary, and any unusual symptoms should be reported. Liver or kidney function abnormalities can occur, so liver and kidney function tests should be performed periodically, and if abnormalities are found, the drug should be discontinued. Gastrointestinal symptoms such as diarrhea, abdominal pain, nausea, and vomiting may occur, and severe colitis may develop, so if symptoms are severe, medical attention should be sought immediately. Respiratory side effects such as interstitial pneumonia may rarely appear, so if breathing difficulties or cough worsen, medical attention should be sought immediately. CNS symptoms such as anxiety, agitation, dizziness, hallucinations, and drowsiness may rarely occur, so caution is necessary. Oral candidiasis or stomatitis may occur during treatment, necessitating good oral hygiene. There may be a bleeding tendency due to vitamin K deficiency, so if bleeding symptoms occur, it should be reported immediately, and vitamin K supplementation may be needed. This drug can interact with other medications, especially drugs that affect the kidneys, anticoagulants, and oral contraceptives, so it is essential to inform the physician or pharmacist if these medications are being taken. The safety of this drug during pregnancy or breastfeeding has not been confirmed, so consultation with a doctor is required before use. It is best to avoid using this drug in neonates, especially infants under one month old, as safety and efficacy have not been established. Elderly patients may have decreased physiological functions, posing a higher risk of side effects, so careful dose adjustments and monitoring of their condition are essential. Some urine tests or blood tests may yield distorted results due to this drug, so caution is needed when interpreting test results. This drug should only be used for the minimum period necessary for the treatment of infections to prevent the development of resistant bacteria, and appropriate medication must be confirmed through sensitivity testing before treatment.

Serious side effects

• Shock
• urticaria
• edema
• dyspnea
• anaphylaxis
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• hepatitis
• jaundice
• acute kidney failure

Mild side effects

• Flushing
• angioedema
• sensory disturbances
• fainting
• hypertension
• vasodilation
• rash
• itching
• fever
• lymphadenopathy

This drug should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is recommended to keep it at room temperature between 1°C to 30°C. Storing it this way helps maintain the drug's effectiveness for a longer period.

Appearance

A hard capsule with a blue upper part and a sky-blue lower part filled with pale yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle, 300 capsules/bottle