Dongseongro Rosuvastatin Tablet 20 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose of 5 mg is administered once daily at any time, regardless of meals. The maintenance dose is 10 mg once daily for most patients, which is adjusted based on LDL cholesterol levels, treatment goals, and patient response every 4 weeks or more, with a maximum increase to 20 mg once daily.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17), the dosage is 5 mg to 20 mg once daily. The dosage should be adjusted according to the individual patient's treatment goals, with adjustments made every 4 weeks or more.

This medication should not be used in certain patients. For example, patients who are allergic to any component of this drug, have severe liver dysfunction, have muscle disorders, have severe kidney impairment, or are pregnant or breastfeeding should not take this medication. Additionally, as this medication can affect muscles, symptoms such as muscle pain or myopathy may occur, so patients at high risk for muscle-related diseases should use it with caution. If symptoms such as muscle pain, weakness, or fever occur during treatment, immediate consultation with a physician is necessary. It can affect liver function, so patients with a history of liver disease or those who consume alcohol excessively should undergo regular liver function tests before and after taking this medication. This medication contains lactose, so patients with lactose intolerance should not take it, and caution is required for patients with certain genetic disorders. This medication can interact with other drugs, so it is advisable to consult a physician or pharmacist, especially when taken with drugs with a high risk of muscle toxicity. Concomitant use with certain medications may increase the blood concentration of this medication, raising the risk of side effects. Women who may become pregnant should use appropriate contraception during treatment and should stop taking the medication immediately if they become pregnant. There is no specific antidote in the case of overdose, so treatment according to symptoms and liver function and muscle enzyme tests are required. Lastly, this medication has been rarely reported to cause serious skin reactions, liver damage, or kidney abnormalities, so if such symptoms occur, immediate notification of healthcare personnel is essential. Caution should be taken as dizziness may occur when driving or operating machinery.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, severe swelling (edema), chest tightness, breathing difficulty, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions, difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe headache

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, rash, myalgia, weakness, hematuria, diarrhea, fatigue, numbness, paresthesia, chest discomfort, loss of appetite, abdominal bloating, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, joint pain, memory loss, peripheral neuropathy, cough, thrombocytopenia, hepatitis, increased transaminases, eosinophilia, and drug reaction with eosinophilia and systemic symptoms (DRESS), lupus-like syndrome

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, at a temperature between 1°C and 30°C. This helps maintain the drug's efficacy and prevents deterioration.

Appearance

Pink round film-coated tablet

Package unit

30 tablets (15 tablets/PTP(AluAlu)×2)