Roxacin M Tablet (Ofloxacin)

Adult dosage

For adults, the usual dosage is 300～600 mg of ofloxacin in 2～3 divided doses daily. For Hansen's disease, the dosage is 400～600 mg of this medication in 2～3 divided doses daily. In principle, it should be used in combination with other antileprosy drugs. Adjust the dosage appropriately according to age and symptoms.

This drug may cause tendon-related diseases such as tendinitis and tendon rupture, so usage should be stopped immediately if these symptoms appear. Peripheral neuropathy or central nervous system symptoms may also occur, so careful monitoring is needed if sensory abnormalities or neurological symptoms arise. Patients with myasthenia gravis may experience worsening symptoms with this drug, so it should not be administered to them. This drug is used only for specific bacterial infections and should only be used when there are no other treatment options available. Elderly patients, those with reduced kidney function, and individuals taking corticosteroids are at higher risk for tendon rupture, so extra caution is necessary. During treatment with this drug, care should be taken to avoid strong sunlight or ultraviolet exposure, and treatment should be stopped immediately if skin rashes or photosensitivity reactions develop. Because of the risk of seizures, patients with a history of seizures or central nervous system disorders must consult a healthcare professional before using this drug. This drug may affect liver and kidney function, so regular monitoring is necessary with prolonged use. Care should be taken when driving or operating machinery, as dizziness or drowsiness may occur. Diabetic patients who require blood sugar control should closely monitor any changes in blood sugar levels while taking this drug, and immediate treatment should be sought if hypoglycemic symptoms arise. It is safer for pregnant or potentially pregnant women and nursing mothers to avoid taking this drug. Children and adolescents during growth have not had the safety of this drug established, so it should not be used in this population. There may be interactions with other medications, so any current medications should be reported, especially when using anticoagulants, hypoglycemic agents, and some antacids. In the case of overdose, immediate medical attention should be sought, and this drug is not removed by hemodialysis, so caution is needed. This drug should be stored in a cool, dry place, and kept out of the reach of children.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reactions, rash, itching, erythema, edema, fever, warmth, photosensitivity reactions, hematuria, acute renal failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, abdominal pain, diarrhea, nausea, vomiting, gastric and abdominal discomfort, cirrhosis, appetite loss, gastric and abdominal pain, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal distension, constipation, dysphagia, gastrointestinal hemorrhage, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, petechiae and ecchymosis, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, elevated ESR, insomnia, dizziness, headache, seizures, tremors, paresthesia, sensory disturbances, sensory reduction, diplopia, neglect, nystagmus, tinnitus, hearing loss, hallucinations, drowsiness, hypersensitivity, sleep disorders, confusion, anxiety, depression, agitation, hyperesthesia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory disturbances, equilibrium disturbances, ataxia, aphasia, heaviness of the head, skin and mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Leal syndrome, arthralgia, myalgia, muscle weakness, myositis, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, pruritus of the external female genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, malaise, fever, aortic aneurysm, aortic dissection, heart valve regurgitation, heart valve insufficiency

This drug should be stored in a sealed container to prevent air or moisture from entering. It is recommended to store it at room temperature, between 1 to 30 degrees Celsius. This helps to maintain the drug's efficacy for a longer period.

Appearance

White to light yellow round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle