Nicover Tablets 1mg (Varenicline Salicylate)

Adult dose

Patients should set a quit date and start taking this medicine 1 week before that date. Alternatively, they may quit smoking between days 8 and 35 after starting this medicine. Take this medicine after meals with plenty of water. Days 1–3 0.5 mg once daily Days 4–7 0.5 mg twice daily Day 8 until the end of treatment 1 mg twice daily For patients unable to tolerate the adverse reactions of this medicine, the dose may be reduced temporarily or permanently. The treatment period is 12 weeks. For patients who successfully quit smoking during the first 12 weeks of treatment, an additional 12 weeks of treatment with this medicine is recommended to increase the likelihood of long-term abstinence. Continue this medicine for an additional 12 weeks, for a total treatment period of 24 weeks. No dose adjustment is required in patients with mild (estimated creatinine clearance > 50 ml/min and ≤ 80 ml/min) to moderate (estimated creatinine clearance ≥ 30 ml/min and ≤ 50 ml/min) renal impairment. In patients with severe renal impairment (estimated creatinine clearance < 30 ml/min), the recommended starting dose of varenicline is 0.5 mg once daily. If needed, the maximum dose is 0.5 mg twice daily. In patients with end-stage renal disease receiving hemodialysis, if well tolerated, a maximum dose of 0.5 mg once daily may be used. No dose adjustment is required in patients with hepatic impairment. Because renal function is more likely to be reduced in elderly patients, care should be taken when selecting the dose, and monitoring renal function may be useful.

Child dose

Use in patients under 18 years of age is not recommended.

This medication can cause psychiatric symptoms and suicidal tendencies, so if symptoms of depression, anxiety, aggression, or suicidal thoughts appear while taking it, you should consult a doctor immediately. This medication must not be administered to patients with hypersensitivity. Women who are pregnant or breastfeeding should use this medication with caution and consult a physician if necessary. Common side effects include nausea, headaches, insomnia, and abnormal dreams, so caution is advised. This medication may provoke seizures, so patients with a history of seizures must consult a doctor before taking it. Caution is required while driving or operating machinery, as drowsiness or decreased concentration may occur. This medication has few interactions with other medications, but alcohol consumption can exacerbate side effects, so it is advisable to minimize or avoid intake. Pregnant and lactating women must use this medication carefully as it may affect the fetus or newborn. Safety and efficacy in children under 18 have not been established, so it is not recommended. Elderly patients may have an increased risk of drug side effects due to decreased kidney function, so dose adjustment and monitoring of renal function are necessary. In case of overdose, standard emergency treatment should be received, and dialysis treatment may be considered if necessary. This medication should be kept out of the reach of children and stored in its original container to prevent misuse or degradation in quality.

suicidal ideation, suicidal behavior, suicide, changes in behavior or thoughts, depression, mania, mood changes, psychosis, aggressive behavior, hallucination, paranoia, delusion, homicidal ideation, hostility, agitation, anxiety, panic state, discomfort, depressed mood, insomnia, irritability, frustration, anger, difficulty concentrating, restlessness, decreased heart rate, increased appetite, weight gain, decreased platelet count, weight gain, decreased appetite, increased appetite, abnormal dreams, insomnia, abnormal thoughts, restlessness, mood changes, decreased libido, discomfort, mental tension, headache, drowsiness, dizziness, taste disturbance, tremor, somnolence, sensory loss, speech disturbance, motor coordination disorder, taste hypesthesia, circadian rhythm sleep disorder, conjunctivitis, eye pain, scotoma, glare, tinnitus, angina, tachycardia, palpitations, increased heart rate, atrial fibrillation, decreased ST segment on electrocardiogram, reduced amplitude of electrocardiogram waves, increased blood pressure, facial flushing, upper respiratory disorders, dyspnea, cough, upper respiratory inflammation, airway congestion, vocal cord dysfunction, allergic rhinitis, throat irritation, sinus congestion, upper respiratory cough syndrome, runny nose, snoring, nausea, gastroesophageal reflux disease, vomiting, constipation, diarrhea, abdominal bloating, abdominal pain, toothache, indigestion, flatulence, dry mouth, bloody stools, gastritis, belching, aphthous stomatitis, gum pain, hematemesis, rash, itching, erythema, acne, hyperhidrosis, arthralgia, myalgia, back pain, muscle spasm, joint stiffness, increased urination, nocturia, diabetes, polyuria, menorrhagia, sexual dysfunction, chest pain, fatigue, chest discomfort, influenza-like illness, fever, weakness, lethargy, liver function test abnormalities, anemia, lymphadenopathy, leukocytosis, thrombocytopenia, splenomegaly, arrhythmia, bradycardia, ventricular extrasystole, myocardial infarction, cardiac arrhythmia, coronary artery disease, pulmonary heart disease, acute coronary syndrome, hearing loss, Ménière's disease, thyroid disease, dry eyes, eye irritation, blurred vision, visual impairment, acquired night blindness, transient visual loss, subcapsular cataract, ocular vascular disease, vitreous floaters, gingivitis, dysphagia, enterocolitis, gastrointestinal bleeding, oral ulcer, esophagitis, peptic ulcer, intestinal obstruction, acute pancreatitis, edema, thirst, chills, gallbladder disease, hypersensitivity reaction, drug hypersensitivity reaction, electrocardiogram abnormalities, increased creatine phosphokinase, urinalysis abnormalities, diabetes mellitus, hyperlipidemia, hypokalemia, hyperkalemia, hypoglycemia, muscle cramps, musculoskeletal pain, arthritis, osteoporosis, myositis, attention deficit disorder, sensory disorders, amnesia, migraine, dysosmia, psychomotor agitation, restless legs syndrome, syncope, balance disorder, cerebrovascular event, convulsion, facial nerve paralysis, mental disorder, multiple sclerosis, eye twitching, psychomotor dysfunction, transient ischemic attack, visual field loss, anxiety, emotional disorder, hypersensitivity, aggression, agitation, disorientation, dissociation, euphoria, suicidal ideation, nephrolithiasis, abnormal urine, urethral syndrome, acute renal failure, urinary retention, menstrual disorders, erectile dysfunction, epistaxis, respiratory diseases, asthma, pleurisy, pulmonary embolism, dermatitis, dry skin, eczema, psoriasis, urticaria, photosensitivity reaction, hypotension, peripheral ischemia, thrombosis, seizure, traffic accident, near traffic accident, drowsiness, dizziness, loss of consciousness, decreased concentration, relief, sleep disorders, increased hypersensitivity, relief, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, sleep disorder, nightmare, excessive dreaming, bedtime disorders, abnormal urine, renal failure, allergic reaction, hypersensitivity response, Stevens-Johnson syndrome, erythema multiforme, ischemic and hemorrhagic reaction, cerebrovascular incident, myocardial infarction, angioedema, hypersensitivity reaction, angioedema, hypersensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, unstable angina, insomnia, anxiety, abnormal thinking, neuritis, syncope, exacerbation of pneumonia, arterial stenosis, feeling fuzzy-headed, unpleasant sensation, mental distress, hair loss, increased sputum, memory impairment, coldness, worsening condition, stimulation, burning sensation, decreased blood pressure, increased blood pressure

This medication must be kept in a tightly sealed container to avoid exposure to air or moisture, and it should be stored at room temperature between 1 to 30 degrees Celsius. Avoid storage in direct sunlight, high-temperature, or humid areas.

Appearance

Light blue, biconvex, film-coated rectangular tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2)