Aiklan Syrup (Amoxicillin and Clavulanate Potassium)

Adult dose

For mild to moderate infections such as recurrent tonsillitis, upper respiratory infections, lower respiratory infections, urinary tract infections, and skin and soft tissue infections, take 20 mg/5 mg per kg of body weight divided into three doses daily. For severe infections such as otitis media, sinusitis, lower respiratory infections such as bronchopneumonia, and urinary tract infections, take 40 mg/10 mg per kg of body weight divided into three doses daily. To minimize potential gastrointestinal intolerance, it is advised to take the medication at the beginning of meals.

Child dose

There is insufficient clinical data on the use of the 4:1 syrup for infants under 2 months of age.

This medication contains the artificial sweetener aspartame, so it should not be used in patients with phenylketonuria, a genetic disorder. Additionally, it should not be administered to patients with a history of hypersensitivity to this medication or beta-lactam antibiotics, patients with infectious mononucleosis or lymphocytic leukemia, patients with a history of liver dysfunction, and patients with genetic problems such as lactose intolerance. Patients with impaired liver function or moderate to severe renal impairment, allergic individuals, elderly patients, and those with gastrointestinal diseases should use this medication cautiously. Gastrointestinal symptoms such as diarrhea, vomiting, abdominal pain, etc. may occur, and rarely, symptoms such as pseudomembranous colitis, liver dysfunction, skin rashes, blood abnormalities, renal impairment, and central nervous system symptoms may occur, so immediate consultation with medical personnel is required if adverse symptoms appear. Long-term use of this medication may lead to the development of resistant bacteria, so it should only be used for the minimum necessary duration for treatment, and it is important to regularly check liver and renal functions. Patients who are allergic to penicillin class drugs or who have experienced severe hypersensitivity reactions in the past should be particularly cautious, and after administration, they should be closely monitored for the occurrence of serious allergic reactions such as anaphylactic shock. This medication may interact with other drugs, so patients taking anticoagulants, certain antibiotics, anti-inflammatory medications, and oral contraceptives should inform their healthcare provider and use it carefully. Women who are pregnant or may become pregnant should consult a physician before using this medication, especially during the first trimester of pregnancy, as it is advisable to avoid its use. Breastfeeding mothers should also be cautious as this medication may cause diarrhea or skin rashes in infants when taken. In pediatric patients, especially in newborns or premature infants under 2 months of age, safety has not been established, so caution is advised when using it. Elderly patients may experience more severe adverse reactions due to declining renal function, so dosage and intervals should be adjusted and administered cautiously. This medication should be refrigerated after preparation and used within 7 days, and it is important to shake well before administration. In cases of overdose, gastrointestinal symptoms or renal impairment and neurological abnormalities may occur, so administration should be stopped immediately and appropriate treatment sought. Finally, if unusual symptoms such as diarrhea, abdominal pain, or skin rashes occur while using this medication, immediate notification of medical personnel is necessary to receive appropriate care.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylactic shock, mucosal and skin syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), blistering exfoliative dermatitis, acute generalized exanthematous pustulosis, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, mucous membrane pain in the mouth/eyes, liver abnormalities (jaundice), sudden and severe headaches, seizures, consciousness.

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, decreased appetite, abdominal pain, bloating, constipation, colonic pain, acid reflux, soft stools, dry mouth, hepatitis, cholestatic jaundice, itching, erythema multiforme, skin rash, dermatitis, serum sickness symptoms (fever, rash, arthralgia, swelling, lymphadenopathy), blood abnormalities (leukopenia, thrombocytopenia, anemia, thrombocytosis, bone marrow suppression), mucosal.

This medication should be kept in a tightly sealed container to prevent moisture, and stored in a cool, dry place below 25 degrees Celsius to maintain its effectiveness. Care should be taken as the components of the medication may degrade in humid or high-temperature areas.

Appearance

A whitish powder with a characteristic odor, this is a syrup to be dissolved and used.

Package unit

50 milliliters/bottle