Medication info
Doxycycline Tablets 100 mg (Doxycycline Hyclate)

Doxycycline Tablets 100 mg (Doxycycline Hyclate)

Prescription medicationTabletOral
Ingredient · strength
Doxycycline Hydrate›100mg / 1 tablet
Manufacturer / importer
Korea HuTex Pharmaceutical Co., Ltd.
Appearance
Green round tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201802879 · Approved 2018.07.11

Summary

Main use
Treatment of bacterial infections (such as pneumonia and cystitis), intestinal amebiasis, and acne
Who takes it
Adults · Children
Adult dose
○ Adults: The initial dose of doxycycline is 100 mg (potency) orally every 12 hours. The maintenance dose is 100 mg (potency) per day, administered in 1 ∼ 2 divided doses. ○ For severe infections, administer the initial dose every 12 hours. Continue administration of this drug for 24 ~ 48 hours after symptoms subside and fever resolves. For streptococcal infections, continue treatment for at least 10 days to prevent the development of rheumatic fever or glomerulonephritis. Adjust the dose as appropriate according to age and symptoms.
Child dose
○ Adolescents aged 12 years and older: For those weighing 45 kg or less, the initial dose is 4 mg (potency) per kg of body weight per day, administered orally in 2 divided doses. The maintenance dose is 2 mg (potency) per kg of body weight per day, administered in 1 ∼ 2 divided doses. ○ Adolescents aged 12 years and older: For those weighing more than 45 kg, administer the dose corresponding to the adult dose.

Ingredients

Manufacturer
Korea HuTex Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of bacterial infections (such as pneumonia and cystitis), intestinal amebiasis, and acne

  • Typhus
  • exanthema
  • Rickettsial disease
  • scrub typhus
  • Q fever
  • Rocky Mountain spotted fever
  • tick fever
  • pneumonia
  • tonsillitis
  • pharyngitis
  • bronchitis
  • bronchiectasis
View approved original text

This medication is effective against various bacterial and Rickettsia infections. It is primarily used for tick-borne diseases such as typhus, scrub typhus, and Rocky Mountain spotted fever, as well as respiratory and systemic infections like Mycoplasma pneumonia, pigeon disease, and parrot fever. Additionally, it is applicable for the treatment of sexually transmitted diseases including syphilis, chancroid, and lymphogranuloma venereum, as well as serious bacterial infections like cholera and plague. Furthermore, it improves symptoms of various infections, including respiratory infections such as tonsillitis, bronchitis, pneumonia, and urinary tract infections like gonorrhea, cystitis, and urethritis, as well as acute dacryocystitis and sinusitis. You should understand that this medication helps treat these bacterial infections, thus being very effective for symptom relief and health recovery.

How to take

Adult dose

○ Adults: The initial dose of doxycycline is 100 mg (potency) orally every 12 hours. The maintenance dose is 100 mg (potency) per day, administered in 1 ∼ 2 divided doses. ○ For severe infections, administer the initial dose every 12 hours. Continue administration of this drug for 24 ~ 48 hours after symptoms subside and fever resolves. For streptococcal infections, continue treatment for at least 10 days to prevent the development of rheumatic fever or glomerulonephritis. Adjust the dose as appropriate according to age and symptoms.

Child dose

○ Adolescents aged 12 years and older: For those weighing 45 kg or less, the initial dose is 4 mg (potency) per kg of body weight per day, administered orally in 2 divided doses. The maintenance dose is 2 mg (potency) per kg of body weight per day, administered in 1 ∼ 2 divided doses. ○ Adolescents aged 12 years and older: For those weighing more than 45 kg, administer the dose corresponding to the adult dose.

Precautions

This medication can cause diarrhea due to Clostridium difficile; if diarrhea occurs, inform your doctor immediately. Severe skin reactions may rarely occur, so if you experience a rash, red spots, or blisters on your skin, stop taking the medication and consult a healthcare professional. People who are allergic to this medication or similar drugs should not take it, and it is advisable that pregnant or breastfeeding women, and children under 12 years old do not use it. Patients with impaired kidney or liver function require dosage adjustments and regular testing while using this drug. This medication may increase sensitivity to sunlight, so it is recommended to avoid direct sunlight and to use sunscreen while on this medication. When taking the medication, swallow it while standing or sitting with plenty of water; especially, it is advisable to avoid taking it just before going to bed as it may increase the risk of esophageal irritation or ulcers. There may be interactions with other medications, so make sure to inform your healthcare provider about any other medications you are taking, particularly oral contraceptives, antacids, anticoagulants, and hepatotoxic drugs. In case of overdose, symptoms such as vomiting, nausea, liver and kidney damage may appear, so be cautious not to exceed the recommended dose, and seek medical attention immediately if unusual symptoms occur. It is important to keep this medication out of reach of children and to store it sealed in its original container.

Side effects

Diarrhea, colitis, exfoliative dermatitis, erythema multiforme, mucocutaneous syndrome, toxic epidermal necrolysis, drug reactions associated with eosinophilia and systemic symptoms, hemolytic anemia, neutropenia, thrombocytopenia, hypersensitivity, anaphylactic shock, angioedema, exacerbation of systemic lupus erythematosus, pericarditis, serum sickness, Henoch-Schönlein purpura, hypotension, dyspnea, tachycardia, peripheral edema, urticaria, thyroid microscopic brown discoloration, decreased appetite, headache, benign intracranial hypertension, nasal polyp protrusion, tinnitus, flushing, nausea, vomiting, dyspepsia, pancreatitis, membranous colitis, esophageal ulcer, esophagitis, enterocolitis, perianal genital inflammatory lesions, dysphagia, abdominal pain, glossitis, tooth discoloration, hepatotoxicity, hepatitis, liver dysfunction, photosensitivity reactions, rash, photo-onycholysis, exfoliative dermatitis, arthralgia, myalgia, increased BUN, anemia, granulocyte decrease, atypical lymphocytes, lymphocyte decrease, lymphadenopathy, blood coagulation disorders, anaphylactic reaction, fever, paresthesia, anxiety, agitation, severe colitis accompanied by blood in stool, loose stools, stomatitis, sore throat, black hairy tongue, hoarseness, jaundice, onycholysis, nail color change, fixed drug eruption, arthritis, kidney damage, interstitial nephritis, acute renal failure, oliguria, hematuria, visual disturbances, papilledema of the optic nerve, decreased or loss of smell and taste, vitamin K deficiency, symptoms of vitamin B complex deficiency, swelling of the face, tongue, and larynx, yellow urine, reduced urine glucose, liver and kidney parenchymal damage, anaphylactic reaction, liver damage, esophagitis, esophageal ulcer, hypersensitivity reaction

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and light, so it should be stored in a tightly sealed container. It should be kept at room temperature, ideally between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

Green round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.