Isentress HD Tablets (Raltegravir Potassium (Unmicronized))

Adult dose

Recommended dose of this medicine in adults - Patients with no prior treatment experience, or - Patients whose virus is suppressed with initial therapy using Isentress 400mg tablets twice daily Take 1200mg (2 tablets of the 600mg formulation) once daily, with or without food * Do not take 1200mg once daily using 400mg tablets instead of 600mg tablets

Child dose

Patients weighing 40kg or more who meet 1 of the following conditions Patients with no prior treatment experience, or - Patients whose virus is suppressed with initial therapy using Isentress 400mg tablets twice daily Take 1200mg (2 tablets of the 600mg formulation) once daily, with or without food * Do not take 1200mg once daily using 400mg tablets instead of 600mg tablets

This drug may cause serious skin reactions and hypersensitivity reactions, so if severe rash, fever, general malaise, fatigue, muscle and joint pain, blisters, oral lesions, conjunctivitis, facial swelling, or liver dysfunction occur, stop taking it immediately and consult a doctor. During the use of this drug, immune reconstitution syndrome, which is an excessive reaction of the immune system, may occur, so if new symptoms develop or existing infections worsen, consult a doctor immediately. The effectiveness of this drug may decrease or increase if taken with antacids or certain antiviral agents, so make sure to inform your doctor or pharmacist if you are taking other medications. Bone tissue damage called osteonecrosis has been reported, so if joint pain or mobility problems occur, notify the medical staff immediately. Patients with a history of depression or mental illness should pay special attention to changes in mental status. Patients with hypersensitivity to this drug or certain genetic disorders such as lactose intolerance should not take it, and it is not recommended for patients with severe liver or kidney dysfunction. Dizziness may occur during use, so caution is needed when driving or operating machinery. Insufficient safety data is available for use during pregnancy, so if pregnant or planning to become pregnant, consult your doctor, and it is advisable to avoid use while breastfeeding. If you forget to take a dose, take it as soon as you remember, but if it is close to the next dose time, skip it and do not take a double dose. This drug should be kept out of reach of children, and in case of overdose, since no specific antidote is available, you should visit a medical institution immediately for appropriate treatment.

Severe skin reactions, hypersensitivity reactions, rash, generalized malaise, fatigue, muscle and joint pain, blisters, oral lesions, conjunctivitis, facial edema, hepatitis, eosinophilia, angioedema, immune reconstitution syndrome, autoimmune diseases, depression, suicidal thoughts and behavior, nausea, fatigue, headache, dizziness, insomnia, abdominal pain, gastritis, dyspepsia, vomiting, weakness, hepatitis, hypersensitivity, genital herpes, herpes zoster, nephrolithiasis, renal failure, rash, myopathy, rhabdomyolysis, thrombocytopenia, diarrhea, hepatic failure, cerebellar ataxia, anxiety, paranoia, psychomotor agitation, abnormal behavior, insomnia, abnormal liver function, increased serum glucose, increased serum bilirubin, increased serum aspartate aminotransferase, increased serum alanine aminotransferase, increased serum alkaline phosphatase, increased creatinine, increased lipase, increased creatine kinase

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is also best to store it at a temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy and safety.

Appearance

Yellow oval film-coated tablets engraved with the MSD logo and '242' on one side

Package unit

60 tablets/bottle