Yuyu Varenicline Salicylate Tablet 0.5 mg

Adult dosage

Usual dosage for adults Patients should set a quit date and start taking this medicine 1 week before that date. Alternatively, they may begin quitting smoking between Day 8 and Day 35 after starting this medicine. The recommended dosage of this medicine is as follows: after 1 week of dose titration, take 1 mg twice daily. Days 1–3 0.5 mg once daily Days 4–7 0.5 mg twice daily Day 8 until the end of treatment 1 mg twice daily For patients who cannot tolerate adverse reactions to this medicine, the dose may be reduced temporarily or permanently. The treatment period is 12 weeks. For patients who successfully quit smoking with the first 12 weeks of treatment, an additional 12 weeks of this medicine is recommended to increase the likelihood of long-term abstinence. Take this medicine for an additional 12 weeks for a total treatment period of 24 weeks. Patients with renal impairment No dose adjustment is necessary in patients with mild (estimated creatinine clearance > 50 mL/min and ≤ 80 mL/min) to moderate (estimated creatinine clearance ≥ 30 mL/min and ≤ 50 mL/min) renal impairment. In patients with severe renal impairment (estimated creatinine clearance < 30 mL/min), the recommended starting dose of varenicline is 0.5 mg once daily. If needed, the maximum dose is 0.5 mg twice daily. In patients with end-stage renal disease receiving hemodialysis, if well tolerated, a maximum dose of 0.5 mg once daily may be administered. Elderly patients and patients with hepatic impairment No dose adjustment is necessary in patients with hepatic impairment.

Children's dosage

Use is not recommended in patients under 18 years of age.

This drug helps with smoking cessation and during usage, serious mental health issues may arise such as depression, suicidal thoughts, aggressive behavior, and hallucinations. Caution is necessary. If these symptoms occur, discontinue use immediately and consult a doctor. Those allergic to this medication should not use it, and women who are pregnant or breastfeeding should use it cautiously. During the initial treatment phase, side effects such as nausea, headache, insomnia, and abnormal dreams may commonly occur, and these symptoms are generally mild or temporary. Patients with cardiovascular disease should consult with a physician before use, as cardiac issues may worsen. Seizures may occur during treatment; therefore, individuals with a history of seizures or those at risk for seizures should consult their doctor before use. The side effects may be exacerbated when taken with alcohol, so alcohol consumption should be avoided or minimized during treatment. Caution is advised when engaging in hazardous activities such as driving or operating machinery until physical responses are assessed after dosing. It is advisable not to use this medication for children, as safety has not been established. Elderly or patients with reduced kidney function may require dosage adjustments, following the physician's instructions. In the case of overdose, seek appropriate medical attention immediately. This medication should be stored in its original container, out of the reach of children.

• suicidal ideation
• suicidal behavior
• depression
• mania
• mood changes
• psychosis
• aggressive behavior
• hallucinations
• paranoia
• delusions

This medication should be stored in a sealed container to prevent exposure to air and moisture, and it is best to store it at room temperature between 1 to 30 degrees Celsius. This will help maintain the efficacy of the medication and prevent degradation.

Appearance

White or grayish-white, double-convex, rectangular film-coated tablet

Package unit

11 tablets (11 tablets/Blister X 1)