Yuyu Varenicline Salicylate Tablet 1 mg

Adult dosage

Patients should set a quit date and start taking this medicine 1 week before that date. Alternatively, they may begin quitting smoking between Day 8 and Day 35 after starting this medicine. This medicine should be taken after meals with plenty of water. The recommended dosage of this medicine is as follows: after 1 week of dose titration, take 1 mg twice daily. Days 1–3 0.5 mg once daily Days 4–7 0.5 mg twice daily Day 8 until the end of treatment 1 mg twice daily For patients who cannot tolerate adverse reactions to this medicine, the dose may be reduced temporarily or permanently. The treatment period is 12 weeks. For patients who successfully quit smoking with the first 12 weeks of treatment, an additional 12 weeks of this medicine is recommended to increase the likelihood of long-term abstinence. For patients who cannot or do not wish to stop smoking abruptly, consider gradually reducing smoking while taking this medicine. Reduce the amount smoked by 50% from the pretreatment level within the first 4 weeks after starting this medicine, and by an additional 50% within the next 4 weeks. Continue reducing the amount smoked to achieve complete smoking cessation by Week 12. Take this medicine for an additional 12 weeks for a total treatment period of 24 weeks. No dose adjustment is necessary in patients with mild (estimated creatinine clearance > 50 mL/min and ≤ 80 mL/min) to moderate (estimated creatinine clearance ≥ 30 mL/min and ≤ 50 mL/min) renal impairment. In patients with severe renal impairment (estimated creatinine clearance < 30 mL/min), the recommended starting dose of varenicline is 0.5 mg once daily. If needed, the maximum dose is 0.5 mg twice daily. In patients with end-stage renal disease receiving hemodialysis, if well tolerated, a maximum dose of 0.5 mg once daily may be administered. No dose adjustment is necessary in patients with hepatic impairment. In elderly patients, renal function is more likely to be reduced, so use caution when selecting the dose; monitoring renal function may be useful.

Children's dosage

Patients under 18 years of age: The safety and efficacy of this medicine have not been established in children; therefore, use is not recommended in patients under 18 years of age.

This drug is a medication to assist with smoking cessation, and care must be taken as it may cause neuropsychiatric symptoms or suicidal tendencies. During treatment, psychic symptoms such as anxiety, depression, aggression, and hallucinations may occur, so if unusual symptoms arise, the treatment should be stopped immediately, and medical advice should be sought. If there is a history of psychiatric disorders, it is essential to inform the physician, and mental status should be carefully monitored before and after treatment. This medication should not be administered to patients with hypersensitivity, and cautious use is required for pregnant or breastfeeding women. Common side effects include nausea, headache, insomnia, and abnormal dreams, so this should be noted. Caution is needed when engaging in dangerous activities such as driving or operating machinery after taking this medication, as drowsiness or dizziness may occur. This medication should also be used cautiously in patients with cardiovascular disease, and if heart-related symptoms arise, the physician should be informed immediately. Alcohol consumption may worsen the side effects of this medication, so it is best to avoid it during treatment. There are few drug interactions, but it is safe to consult a physician when taking other medications. It is not recommended for pediatric patients or adolescents under 18 years of age, and the dosage may need to be adjusted for the elderly according to kidney function. In case of overdose, medical attention should be sought immediately. This medication should be stored out of reach of children and kept in its original container to maintain quality.

• Suicidal ideation
• suicidal behavior
• suicide
• changes in behavior or thought
• depression
• mania
• mood changes
• psychosis
• aggressive behavior
• hallucinations

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius to safely preserve its efficacy.

Appearance

Light blue, biphasic, convex, rectangular film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)