Ciprofloxacin Tablets (Ciprofloxacin Hydrochloride Hydrate)

Adult dose

For adults, ciprofloxacin should be taken orally at a dose of 250-500 mg twice a day between meals. In cases of severe complicated infections, the dose may be increased to 750 mg twice a day. For acute infections, treatment usually lasts for 5-10 days, and even after symptoms have resolved, it should be continued for at least 3 additional days. Patients with renal impairment should have their doses adjusted according to creatinine clearance, and even patients with severe renal impairment can have their dose increased to 750 mg for severe infections.

This drug may cause serious side effects, such as tendonitis, tendon rupture, peripheral neuropathy, central nervous system adverse reactions. If such symptoms occur, immediately discontinue use and consult a physician. Patients with myasthenia gravis may experience worsening symptoms if they use this drug, so it should not be administered. This drug is only used in limited cases such as acute bacterial sinusitis, acute exacerbation of chronic bronchitis, simple urinary tract infections, and acute otitis media. Particularly, elderly patients, those with impaired kidney function, transplant patients, and those taking corticosteroids are at increased risk of tendon rupture and should be cautious. Co-administration with corticosteroids should be avoided, and if tendon pain or inflammation occurs, the medication should be discontinued immediately, and rest should be taken. This drug increases the risk of seizures, hence should be used carefully in patients with epilepsy or central nervous system disorders. This drug is not to be administered to pregnant or nursing women, children under 18 years of age, patients with epilepsy, or those allergic to this drug or similar medications. Moreover, concomitant use with certain medications such as tizanidine or ketoprofen is not advised due to the risk of side effects. Patients with severe renal impairment, the elderly, or those with a history of seizures should exercise extra caution when using this drug. This drug can cause various serious adverse reactions, so if symptoms such as skin rash, liver function abnormalities, psychiatric symptoms, visual disturbances, myalgia, renal abnormalities occur during administration, the physician should be immediately informed. While taking this medication, avoid strong sunlight or ultraviolet exposure, and if photo-sensitivity reactions are suspected, discontinue administration. Blood sugar changes may occur, so diabetic patients should monitor their blood sugar levels carefully. This drug can interact with several other medications, so if there are other medications being taken, it is imperative to inform the healthcare provider. Pregnant or nursing women should preferably avoid using this drug, and it is also not to be administered to children or growing adolescents. Elderly patients may have higher concentrations of this drug due to renal function decline, requiring dosage adjustments. In cases of overdose, renal function should be monitored closely and emergency treatment should be administered if necessary. This drug should be stored away from direct sunlight and ultraviolet light, and kept out of reach of children.

Serious side effects

Tendonitis, tendon rupture, peripheral neuropathy, central nervous system effects, worsening of severe myasthenia gravis, anaphylactic reactions, anaphylactic-like reactions shock, serum sickness-like reactions, bone marrow suppression, liver function test abnormalities, liver dysfunction, jaundice, cholestatic jaundice, liver necrosis, skin and mucosal membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, seizures, delirium, convulsions, coma, shock, hypotension, respiratory distress.

Mild side effects

• Nausea
• diarrhea
• loss of appetite
• gastrointestinal discomfort
• vomiting
• gastrointestinal and abdominal pain
• abdominal bloating
• indigestion
• headache
• dizziness

This drug should be stored in a sealed container to prevent air or moisture ingress. Additionally, storing it in a temperature range of 1 to 30 degrees Celsius is the safest.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle