Medication info
Cregojung 5 mg (Rosuvastatin Calcium)

Cregojung 5 mg (Rosuvastatin Calcium)

Prescription medicationTablet
Ingredient · strength
Rosuvastatin Calcium›5.2mg / 1 tablet
Manufacturer / importer
일양약품(주)
Appearance
Yellow round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201801342 · Approved 2018.03.27 · Insurance code 641705430

Summary

Main use
Treatment for hypercholesterolemia and reduction of cardiovascular disease risk
Who uses it
Adults · Children
Adult dosage
Administer 5 mg once daily as the initial dose, regardless of meals. If greater LDL cholesterol reduction is required, adjust to a maintenance dose of 10 mg once daily, titrating as appropriate based on LDL levels and patient response at intervals of 4 weeks or more. The maximum daily dose can be increased to 20 mg.
Children's dosage
For children aged 10 to 17 years, the dosage ranges from 5 mg to 20 mg once daily. The dosage should be adjusted based on individual treatment goals at intervals of 4 weeks or more. At age 10

Ingredients

Manufacturer
일양약품(주)

Efficacy & effects

Treatment for hypercholesterolemia and reduction of cardiovascular disease risk

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • primary dysbetalipoproteinemia
  • increased high-sensitivity C-reactive protein
  • hypertension
  • low HDL cholesterol levels
  • smoking
  • family history of early coronary heart disease
View approved original text

This medication is primarily used as an adjunct to diet for patients with primary hypercholesterolemia and mixed dyslipidemia. It is especially helpful in cases where dietary and exercise measures are insufficient to control cholesterol. It is also administered in conjunction with other treatments for patients with homozygous familial hypercholesterolemia. This medication helps lower total cholesterol and LDL cholesterol levels in patients with hypercholesterolemia, thereby delaying the progression of atherosclerosis. It is effective for pediatric patients with specific criteria for heterozygous familial hypercholesterolemia. Additionally, it is used in the treatment of primary dysbetalipoproteinemia. In some adult patients with high cardiovascular risk, it contributes to reducing the risk of stroke, myocardial infarction, and arterial revascularization. This medication is used to improve cholesterol levels and reduce the risk of cardiovascular diseases.

Dosage and Administration

Adult dosage

Administer 5 mg once daily as the initial dose, regardless of meals. If greater LDL cholesterol reduction is required, adjust to a maintenance dose of 10 mg once daily, titrating as appropriate based on LDL levels and patient response at intervals of 4 weeks or more. The maximum daily dose can be increased to 20 mg.

Children's dosage

For children aged 10 to 17 years, the dosage ranges from 5 mg to 20 mg once daily. The dosage should be adjusted based on individual treatment goals at intervals of 4 weeks or more. At age 10

Precautions

This medication should not be used in certain patients. For example, patients with an allergy to this medication, severe liver problems, muscle disorders, severe kidney impairment, women who are pregnant or breastfeeding, and fertile women who do not use adequate contraception should not be treated with this medication. Additionally, caution should be exercised when administering this medication to patients at high risk of muscle-related side effects. Risk factors include moderate to severe kidney dysfunction, hypothyroidism, family history of muscle disorders, excessive alcohol consumption, and concomitant use of certain medications. It is important to regularly monitor liver function and muscle health during treatment with this medication. If there are abnormal elevations in liver enzyme levels or symptoms such as muscle pain, weakness, or cramps, immediate consultation with a physician is necessary. This medication can interact with other drugs, so it is essential to inform healthcare providers about any other medications being taken. The risk of muscle damage may increase when used in combination with certain antibiotics, antifungals, immunosuppressants, and fibrate medications. Women who are pregnant or planning to become pregnant should not take this medication, and it should be avoided in breastfeeding women as well, due to potential risks to the fetus and infant. In case of overdose, there is no specific antidote, so one should seek immediate medical attention for appropriate treatment and monitoring. Lastly, this medication may rarely cause serious skin reactions or liver damage, so if symptoms such as rashes, jaundice, or severe fatigue occur, discontinuation of the medication and consultation with healthcare providers is necessary.

Side effects and when to seek care immediately

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptom drug reaction syndrome, rhabdomyolysis, myopathy (including myositis), immune-mediated necrotizing myopathy, acute renal failure, oliguria, chest tightness, difficulty breathing, severe muscle weakness, ocular muscle weakness, jaundice, hepatitis, fatal and non-fatal liver failure, dyspnea, severe allergic reactions, severe edema, or

Mild side effects

  • Headache
  • dizziness
  • constipation
  • nausea
  • abdominal pain
  • itching
  • rash and urticaria
  • myalgia
  • weakness
  • diarrhea
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  • chest discomfort
  • loss of appetite
  • abdominal bloating
  • abnormal liver function tests
  • joint pain
  • fatigue
  • numbness
  • sensory abnormalities
  • fainting
  • generalized pain
  • muscle cramps
  • gout
  • erectile dysfunction
  • hematuria
  • thrombocytopenia
  • memory loss
  • peripheral neuropathy
  • cough
  • ocular muscle weakness
  • depression
  • sleep disturbances
  • sexual dysfunction
  • gynecomastia
  • cognitive impairment

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from exposure to air and moisture. It is best to maintain the storage temperature between 1°C and 30°C at room temperature. This ensures the medication's effectiveness is preserved safely.

Appearance and packaging

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.