Almaphron Tablets (Limaprost Alfadex)

Adult dose

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness caused by thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability caused by acquired lumbar spinal canal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted appropriately according to age and symptoms.

This medication should not be administered to women who are pregnant or may become pregnant. This medication contains lactose, so it should not be used in patients with hereditary diseases that prevent lactose digestion. It should be carefully administered to patients who have a tendency to bleed or are taking medications that affect blood coagulation. During the use of this medication, hypersensitivity reactions such as skin rashes or itching may occur, and if such symptoms appear, administration should be discontinued immediately. Bleeding may rarely occur, so if any bleeding symptoms arise, stop using the medication immediately and consult medical personnel. Gastrointestinal symptoms such as diarrhea, nausea, abdominal pain, and loss of appetite may occur; if symptoms persist, please inform. This medication may affect liver function and could potentially elevate liver enzyme levels; therefore, regular testing and monitoring are necessary. Palpitations, hypotension, and symptoms such as cyanosis of the extremities may occur rarely, so careful observation is required. Various symptoms such as headaches, facial flushing, dizziness, heat sensation, tremors, and swelling may occur; please inform if you notice any of these abnormal symptoms. Patients with lumbar spinal canal stenosis should closely monitor changes in symptoms and decide on the continuation of the medication. The effectiveness of this medication in cases of severe spinal canal stenosis requiring surgery has not been definitively proven. Safety during pregnancy has not been established, and uterine contractions have been reported in animal experiments, so pregnant women should not use it. Safety in children has not been confirmed, so this medication should not be administered to children. Elderly patients may have reduced bodily functions, so caution is needed regarding dosage adjustments. Administration of high doses to healthy adults may temporarily lower blood pressure, so caution should be exercised.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication should be stored in a sealed container to protect it from exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to effectively preserve the medication's effectiveness and ensure safe use.

Appearance

White round tablet

Package unit

84 tablets/Alu-Alu((21 tablets/Alu-Alu)X4)