Restain Eye Drops 0.05% (Cyclosporine) (Single Use)

Adult eye dose

Instill 1 drop into each eye twice daily, approximately 12 hours apart. If using this medicine at the same time as artificial tears, allow an interval of 15 minutes between administrations. Discard any remaining solution and the container after instillation.

This medication should be used with caution in patients with a history of herpes keratitis, as sufficient research has not been conducted. The effect of increased tear production has not been observed in patients using topical anti-inflammatory agents or tear plugs. Patients with active ocular infections or known or suspected allergic reactions to this medication should not use it. The most common side effect is a burning sensation in the eyes, while conjunctival hyperemia, discharge, eye pain, foreign body sensation, itching, and vision disturbances may occur rarely. In severe cases, serious allergic reactions such as eye swelling, angioedema, and difficulty breathing may occur, and in such instances, immediate consultation with healthcare professionals is required. This medication is for ophthalmic use only, and care should be taken to prevent infection or damage by avoiding direct contact of the tip of the container with the eye. There is insufficient safety data on its use during pregnancy; therefore, it should be used cautiously only when necessary, and caution is also required during breastfeeding. Safety and efficacy in pediatric patients under 16 years have not been established, so its use is not recommended. The product should be used immediately after opening, and any remaining solution and container should be discarded. When wearing contact lenses, they should be removed before application and can be reinserted at least 15 minutes later. Keep this product out of reach of children to prevent accidental ingestion. Some trends in cancer occurrence were reported in long-term high-dose oral administration studies; however, the local dosage of this medication is much lower, generally posing a low risk. No special harmful effects were found in mutagenicity or genotoxicity tests, but the possibility of adverse reactions should always be kept in mind during use.

• burning sensation in the eyes
• conjunctival hyperemia
• discharge
• epiphora
• ocular pain
• foreign body sensation
• itching
• pain in the eye
• visual disturbances
• blurred vision

Store this medication in a tightly sealed container to avoid exposure to air or moisture. It is best to maintain a storage temperature between 1 to 30 degrees Celsius to safely preserve the effectiveness of the medication.

Appearance

A colorless or pale white transparent liquid in a colorless transparent plastic single-use container

Package unit

0.4mL/tube × 30 tubes