Cefutil Tablet 250 mg (Cefuroxime Axetil)

Adult dose

For optimal absorption, take after meals. Adults and children 12 years of age and older — most infections: Administer 250mg per dose 2 times daily. Adults and children 12 years of age and older — severe lower respiratory tract infections, pneumonia, severe infections, or infections suspected to be caused by less susceptible organisms: Administer 500mg per dose 2 times daily. Adults and children 12 years of age and older — urinary tract infections: Administer 250mg per dose 2 times daily. Adults and children 12 years of age and older — uncomplicated gonorrhea: Administer 1g as a single dose. Adults and children 12 years of age and older — Lyme disease: Administer 500mg per dose 2 times daily for 14 days (10~21 days). For the treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this medicine should be administered for 7~10 days. Patients with renal impairment: Cefuroxime is primarily eliminated by the kidneys. To compensate for delayed elimination in patients with significantly impaired renal function, reducing the dose of cefuroxime as follows is recommended. ≥ 30 mL/min/1.73m2 (T1/2 1.4 - 2.4 hours): No dosage adjustment required (standard dose: 125mg-500mg per dose 2 times daily) 10 - 29 mL/min/1.73m2 (T1/2 4.6 hours): Administer the standard single dose every 24 hours < 10 mL/min/1.73m2 (T1/2 16.8 hours): Administer the standard single dose every 48 hours Patients receiving hemodialysis (T1/2 2 - 4 hours): Administer an additional standard single dose at the end of each dialysis session

Child dose

Infants and children under 12 years of age — most infections: Administer 125mg per dose 2 times daily. Children 2 years of age and older — otitis media, severe infections: Administer 250mg per dose 2 times daily. Infants and children under 12 years of age — Lyme disease: Administer 250mg per dose 2 times daily for 14 days (10~21 days). Infants under 3 months of age: There is insufficient experience with use. Not suitable for treating patients who cannot swallow tablets, such as young infants and children.

This medication should not be administered to patients with hypersensitivity to cephalosporin antibiotics. Patients with a history of allergies to penicillins or other beta-lactam antibiotics should use it with caution. Caution is also necessary for individuals with bronchial asthma or a tendency to develop allergic symptoms such as skin rashes and urticaria. Patients with severely impaired kidney function should be particularly careful when using this drug. Patients who cannot take oral medications, those receiving parenteral nutrition, elderly patients, and those in poor general condition may show symptoms of vitamin K deficiency, and careful monitoring is needed. When using this medication, hypersensitivity reactions may occur, such as skin rashes, urticaria, itching, fever, serum sickness, and anaphylaxis, and if symptoms arise, medical personnel should be notified immediately. Commonly observed symptoms include headache, dizziness, diarrhea, nausea, abdominal pain, skin rash, itching, thrombocytopenia, leukopenia, vomiting, dyspepsia, constipation, loss of appetite, abdominal bloating, fever, cough, dyspnea, transient increase in liver enzymes, symptoms of vitamin K deficiency, symptoms of vitamin B deficiency, ear pain, peripheral sensation changes around the mouth, tongue numbness, dysphagia, dry mouth, palpitations, eczema, and Churg-Strauss syndrome. Prolonged use may lead to problems caused by excessive proliferation of Candida species or non-susceptible strains, necessitating discontinuation of use if symptoms occur. Diarrhea occurring during or after antibiotic use may indicate the possibility of pseudomembranous colitis, and if there are severe abdominal pains or persistent diarrhea, treatment should be stopped immediately and further evaluation is required. Pregnant women should only use this medication if absolutely necessary, as its safety has not been established, and nursing mothers should also be cautious as the drug can be transmitted through breast milk. The safety of this drug has not been established in children, especially infants under 3 months of age, and due to the strong bitter taste when crushed, syrup formulation is recommended. Elderly patients can develop adverse reactions more easily due to declining body function, so dosage and administration intervals should be adjusted, and careful observation is required. This medication may cause dizziness when driving or operating machinery, thus caution is needed. In cases of overdose, seizures may occur and immediate medical assistance should be sought, with hemodialysis or peritoneal dialysis available to lower drug concentration. Store this medication out of reach of children, and keep it sealed in the original container.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• anemia
• hemoglobin decrease
• hematocrit decrease
• hemolytic anemia

Store this medication in a tightly sealed container that is well-ventilated and should preferably be kept at room temperature between 1 to 30 degrees Celsius. This storage condition helps to maintain the drug's effectiveness for longer.

Appearance

White oval film-coated tablet

Package unit

50 tablets (10 tablets/PTP × 5)