Huviaxone 500 mg (Ceftriaxone Sodium Hydrate)

Adult administration

Adults and children over 12 years should receive 1–2 g (potency) of ceftriaxone once daily via intravenous or intramuscular injection. For infections caused by severe pathogens or moderately sensitive organisms, the dose may be increased up to 4 g (potency) once daily. Elderly patients do not need a dosage adjustment and can follow the adult regimen. For the treatment of gonorrhea, a single intramuscular injection of 250 mg (potency) is recommended. For infections before and after surgery,

Child administration

In neonates (aged 14 days or younger), administer 20–50 mg (potency) per kg of body weight once daily, and do not exceed 50 mg (potency) per kg of body weight. Children and infants (aged 15 days to 12 years) should receive a dosage of

This medication should not be mixed with solutions that contain calcium or other drugs. Especially in neonates, administering it together with calcium can precipitate severe side effects; therefore, it must never be administered. Patients with allergies to this drug or a history of hypersensitivity to cephalosporins or penicillin antibiotics should not use it. Moreover, those allergic to the local anesthetic lidocaine should avoid intramuscular injections, and this drug containing lidocaine should not be used for intravenous administration. Neonates expected to have bilirubin binding disorders, as well as neonates receiving calcium-containing solutions, should also refrain from using this drug. Patients with a history of allergic reactions to this drug or similar antibiotics, those with allergic constitutions, and those with severe kidney diseases should be very cautious when using it, and dosage adjustments or administration intervals may be necessary as needed. This drug can affect blood test results; therefore, regular testing is required, and special caution should be taken as symptoms of vitamin K deficiency may appear. If allergic symptoms or adverse reactions such as rashes, hives, difficulty breathing, dizziness, or vomiting occur during administration, discontinue use immediately and consult a physician. This drug can affect liver and kidney function, so it is important to regularly check liver and kidney function. If diarrhea or abdominal pain occurs after antibiotic use, there is a possibility of Clostridium difficile infection, which requires prompt diagnosis and treatment. This drug should be administered with caution to pregnant or breastfeeding women, as its safety regarding fetuses or neonates has not been fully established. Elderly patients may experience side effects more frequently due to diminished physical function, so adjustment of dosage and administration intervals, and careful monitoring of their condition is necessary. This drug may cause side effects such as dizziness when driving or operating machinery, so caution is required. There may be drug interactions, so if this medication is taken with other drugs, it is essential to consult with a physician or pharmacist. The prepared solution should be used as soon as possible, and storage conditions regarding temperature and time should be strictly observed.

Serious side effects

Hives, severe swelling (edema), anaphylaxis and anaphylactoid reactions, severe allergic reactions, severe skin adverse reactions (erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis), difficulty breathing, asthma attacks, liver abnormalities (jaundice), acute renal failure, serious neurological symptoms (encephalopathy, seizures, tonic-clonic muscle spasms, status epilepticus), severe edema or urinary abnormalities (with hypertension)

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• pruritus
• headache
• dizziness
• bronchospasm

This drug should be stored in a sealed container to prevent air ingress and is recommended to be stored at room temperature between 1 degree and 30 degrees. Storing in this manner helps maintain the medication's effectiveness and prevents deterioration.

Appearance

A colorless, transparent vial filled with white to pale yellow crystalline powder

Package unit

1 vial, 10 vials