Genewon Physiological Saline Injection (Sodium Chloride)

Adult administration

As sodium chloride, typically 20–1,000mL is administered subcutaneously, intravenously, by drip infusion, or rectally. The dosage and infusion rate should be adjusted appropriately based on age, weight, and symptoms.

This medication may introduce glass particles when using glass ampoules, so care must be taken when cutting the ampoule. Particular caution should be exercised when administering to children and the elderly. This medication should not be used in patients with hypernatremia, fluid overload conditions, edema, and cirrhosis with ascites. It should be used cautiously in patients with cardiac and circulatory system dysfunctions, renal impairments, hypoproteinemia, hyponatremia, hypokalemia, and hyperchloremia. Caution is also necessary for patients with peripheral or pulmonary edema, preeclampsia, patients undergoing treatment related to aldosteronism or sodium excretion, children, and the elderly. Rapid or large-volume administration may result in side effects such as congestive heart failure, edema, acidosis, and serum electrolyte abnormalities. During the administration process, side effects such as fever, injection site infection, local pain, phlebitis, extravasation, and volume overload may occur. If adverse reactions occur, administration should be stopped immediately, and the patient should be assessed for appropriate management. During non-oral treatments, fluid balance, electrolyte concentration, and acid-base balance changes should be monitored periodically. Special caution is needed when administering to pregnant women, breastfeeding women, women of childbearing age, newborns, infants, children, and the elderly, particularly for the elderly, where the infusion rate should be slowed, and the dosage adjusted. The container of this medication is made of PVC material containing DEHP, but the risk of exposure to DEHP is very low, so there is no need to avoid its use. During preparation, ensure that the medication is adequately dissolved and check for any color changes or precipitates before administration. Before administration, the patient's skin and tools should be sanitized, and in cold weather, the medication should be warmed to body temperature before use. After opening or mixing with other medications, use immediately and discard any remaining medication. When administering, infuse slowly to reduce the risk of side effects.

Serious side effects

• Congestive heart failure
• edema
• acidosis
• serum electrolyte abnormalities

Mild side effects

Fever, infection at the injection site, local pain or reaction, venous irritation, venous thrombosis or phlebitis leading from the injection site, extravasation, volume overload

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is recommended to store it at room temperature between 1°C and 30°C. Proper storage will help maintain the drug's effectiveness for a longer period.

Appearance

A colorless and transparent injectable solution filled in a clear plastic container packaged with translucent high-density polyethylene or in a colorless and transparent glass container.

Package unit

50mL/box, 100mL/box, 110mL/box, 20mL X 10 vials