Medication info

Kobi C Injection (Ascorbic Acid)

Prescription medication정맥Approval withdrawn
Ingredient · strength
Ascorbic Acid›500mg / 1mL
Manufacturer / importer
한국유나이티드제약(주)
Appearance
A brown vial containing a transparent colorless or pale yellow injection solution
Packaging
20mL x 10 vials
Approval status
Approval withdrawn

MFDS item code 201708355 · Notified 2017.12.13

This product's status changed to Approval withdrawn on 2024.09.30. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Prevention of vitamin C deficiency and treatment of scurvy, promotion of capillary hemorrhage and bone union
Who receives it
Adults
Adult administration
As ascorbic acid, administer 50 to 1,000 mg per day, split into one to several subcutaneous, intramuscular, or intravenous injections. Adjust as appropriate based on age and symptoms.

Ingredients

Manufacturer
한국유나이티드제약(주)

Efficacy & effects

Prevention of vitamin C deficiency and treatment of scurvy, promotion of capillary hemorrhage and bone union

  • Scurvy
  • vitamin C deficiency
  • capillary hemorrhage
  • epistaxis
  • gum bleeding
  • hematuria
  • fractures
  • melasma
  • freckles
  • post-inflammatory hyperpigmentation
  • photosensitive dermatitis
View approved original text

This medication is primarily used for the prevention and treatment of diseases such as scurvy caused by vitamin C deficiency. It is also helpful in situations where the need for vitamin C increases, such as during pregnancy, lactation, and intense physical labor. Additionally, it plays an important role in skin and vascular health, providing relief for symptoms such as capillary bleeding, epistaxis, and gum bleeding. It aids in the recovery of bones by promoting bone matrix formation and union in cases of fractures. It is also effective in improving skin conditions such as melasma, freckles, post-inflammatory hyperpigmentation, and photosensitive dermatitis. This medication is used to improve various vitamin C deficiencies and related symptoms.

How it is given

Adult administration

As ascorbic acid, administer 50 to 1,000 mg per day, split into one to several subcutaneous, intramuscular, or intravenous injections. Adjust as appropriate based on age and symptoms.

Precautions

Care must be taken when cutting the ampoule container for injection as glass fragments may mix in. Extra caution is needed when using this medication on children and the elderly. Patients with allergies to the ingredients in this medication, hyperoxaluria, thalassemia, gout, cystinuria, and G6PD deficiency should not use this medication. Patients with oxalate stones in the kidneys should not exceed a dosage of 1g per day. Side effects such as nausea, vomiting, diarrhea, heartburn, abdominal cramps, fatigue, flushing, headache, and insomnia may occur when using this medication. Dosages above 1g per day may increase the risk of diarrhea and kidney stones, and doses over 600mg may result in diuretic effects. Patients with G6PD deficiency may experience hemolytic anemia. Excessive dosage can lead to the deposition of urate or oxalate in the urinary tract, causing problems. This medication is usually taken orally, but if gastrointestinal absorption is difficult or in urgent situations, it can be administered by injection, transitioning to oral administration as soon as feasible. Co-administration with certain medications, such as salicylates, may reduce the effectiveness of this drug, so concurrent use should be avoided. Furthermore, high doses may decrease the effect of certain anticoagulants and may affect drug concentrations when used with specific psychiatric medications. During pregnancy, the safety for the fetus is not confirmed, so it should only be used when necessary and high doses above 1g should be avoided. During lactation, it is generally considered safe at standard dosages for the infant. This medication may affect the results of urine or blood tests; inform your physician during testing. In case of overdose, symptoms like diarrhea and kidney stones may arise; discontinue use immediately and seek appropriate treatment if symptoms occur. When administered by injection, there may be pain at the injection site; switching injection sites and slowing the injection speed is recommended. Special care is needed, particularly when administering to newborns or young children. Store this medication out of reach of children, avoiding direct sunlight and in a dry place. Additionally, it should be stored in its original container to prevent misuse or quality degradation.

Side effects and when to seek care immediately

Serious side effects

Possible hemolysis in patients with G6PD deficiency

Mild side effects

Nausea, vomiting, diarrhea, heartburn, abdominal cramps, fatigue, flushing, headache, insomnia, temporary mild pain at the injection site, dizziness, vascular pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in an opaque container. Furthermore, to maintain its efficacy, it should be stored at refrigeration temperatures between 2 degrees and 8 degrees.

Appearance and packaging

Appearance

A brown vial containing a transparent colorless or pale yellow injection solution

Package unit

20mL x 10 vials

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.