Medication info
Neurocabapine Capsule 300 mg (Pregabalin)

Neurocabapine Capsule 300 mg (Pregabalin)

Prescription medicationHard capsule
Ingredient · strength
Pregabalin›300mg / 1 capsule
Manufacturer / importer
삼진제약(주)
Appearance
A hard capsule with a reddish-brown upper part and white lower part containing a white to pale yellow powder.
Packaging
30C/bottle
Approval status
Active

MFDS item code 201708174 · Approved 2017.11.30 · Insurance code 647804600

Summary

Main use
Relief of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, treatment of fibromyalgia
Who uses it
Adults · Children
Adult dosage
This medication is to be taken orally, divided into two doses daily, regardless of food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain: The starting dose is 150 mg per day, which may be increased to 300 mg within 3 to 7 days. If necessary, it may be further increased to a maximum of 600 mg per day at intervals of 7 days. 2) Central Neuropathic Pain: The starting dose is 150 mg per day.
Children's dosage
Safety and efficacy data are insufficient for children under 12 years and adolescents aged 12 to 17, so administration is not recommended.

Ingredients

Manufacturer
삼진제약(주)

Efficacy & effects

Relief of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, treatment of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • epilepsy
  • secondary general symptoms
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used to relieve peripheral and central neuropathic pain in adults. It is also utilized as an adjunct treatment for partial seizures in patients with epilepsy, with or without secondary general symptoms. Furthermore, it is effective in relieving symptoms in patients with fibromyalgia, aiding overall pain management. It is used to treat a variety of neurological pain and epilepsy symptoms.

Dosage and Administration

Adult dosage

This medication is to be taken orally, divided into two doses daily, regardless of food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain: The starting dose is 150 mg per day, which may be increased to 300 mg within 3 to 7 days. If necessary, it may be further increased to a maximum of 600 mg per day at intervals of 7 days. 2) Central Neuropathic Pain: The starting dose is 150 mg per day.

Children's dosage

Safety and efficacy data are insufficient for children under 12 years and adolescents aged 12 to 17, so administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so patients should immediately inform healthcare professionals if they experience mood changes or depressive symptoms while taking it. It should not be taken if there is an allergy to any component in this drug. Patients with diabetes may experience weight gain during treatment, which may require adjustments to their blood sugar control medications. If symptoms such as swelling of the face, neck, or around the mouth, or difficulty breathing occur, patients should immediately stop taking the medication and consult a healthcare professional. Elderly patients should be cautious as dizziness or drowsiness may increase, raising the risk of falls or injuries. This medication may cause blurred vision or changes in vision; patients should inform healthcare professionals if these symptoms occur. Abruptly discontinuing this medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so it should be tapered off gradually under the guidance of a healthcare professional. There is a risk of drug abuse; patients with a history of substance abuse should exercise particular caution, and any abnormal behaviors during use should be reported immediately. Patients with impaired kidney function may need a dosage adjustment for this medication. Patients with heart conditions should take this medication with caution, and if symptoms of heart failure occur, they should consult a healthcare professional. Taking this drug with other medications that have central nervous system depressant effects may increase the risk of drowsiness or respiratory depression, so caution is warranted. Pregnant women are advised not to take this medication in the early stages of pregnancy due to potential effects on the fetus, and fertile women should use effective contraceptive methods. Breastfeeding women should consider discontinuing breastfeeding or stopping the medication, as it may pass into breast milk. Activities requiring alertness, such as driving or operating machinery, should be avoided until dizziness or drowsiness from this medication resolves. If severe skin rashes, swelling, or breathing difficulties occur, patients should immediately stop the medication and inform their healthcare professional. In case of overdose, symptoms such as confusion, drowsiness, depression, or seizures may occur, necessitating immediate emergency treatment, and blood dialysis may be performed if needed. This medication should be kept out of reach of children, and transferring it to other containers is discouraged.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema, facial swelling, swelling around the mouth and upper airways), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), pronounced lethargy, dizziness

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • impaired sense of direction
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • altered sexual sensation
  • restlessness
  • anxiety
  • mood swings
  • emotional blunting
  • elevated mood
  • difficulty finding the right words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • affective flattening
  • ataxia
  • abnormal coordination
  • balance disorders
  • memory loss
  • attention disturbances
  • memory impairment
  • tremors
  • speech disturbances
  • sensory disturbances
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is safest to store it at room temperature between 1°C and 30°C. Proper storage maintains the drug's effectiveness and prevents deterioration.

Appearance and packaging

Appearance

A hard capsule with a reddish-brown upper part and white lower part containing a white to pale yellow powder.

Package unit

30C/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.