Pain Solu Joo (Nepufam Hydrochloride)

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, it is advisable to have the patient lie still and rest for 15-20 minutes. When administered in an infusion solution such as electrolytes or glucose, administer 30 mg over 4 hours or 40 mg over 6-8 hours, according to the infusion duration. It is recommended to avoid mixing this medicine with other medicines for injection. The dosage may be adjusted according to age and symptoms.

This medication is an ampule injection and care should be taken when opening the container, as glass fragments may enter the solution. It should not be used in patients with epilepsy, myocardial infarction, those taking MAO inhibitors, those who are allergic to this medication or its components, children under 15 years old, patients with a history of seizures, patients with urinary difficulties due to urethral and prostate problems, and patients with angle-closure glaucoma. Elders, pregnant and breastfeeding women, and those taking anticholinergic medications should use this medication with caution. Using this medication may cause decreased appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, increased heart rate, thirst, urinary retention, pain at the injection site, headache, blurred vision, fatigue, nervousness, sleep disturbances, hallucinations, drug dependency, seizures, and allergic reactions. Side effects vary with dosage and usually resolve with repeated dosing. This medication is used to treat inflammation or pain but is not a treatment for the underlying cause, so it should be administered considering the severity of acute inflammation and pain, and long-term use of the same medication should be avoided. When used for infection-induced inflammation, it should be used cautiously alongside antimicrobial or antifungal agents, particularly in the elderly who should be careful of side effects at minimal doses. Patients with impaired liver and kidney function may be affected by the metabolism and excretion of this medication. This medication can cause drowsiness or decreased concentration, so it is advisable not to use it when driving or operating machinery. Concurrent use with other analgesics or specific medications may increase the risk of side effects, so it is essential to consult a specialist. The use of this medication in pregnant or breastfeeding women is not recommended, and safety has not been established in children under 15 years old, so it should not be used. In the elderly, this medication is also not recommended due to anticholinergic side effects. In the case of overdose, there may be issues with the heart and respiration; therefore, immediate consultation with medical personnel is necessary, and mixing this medication with other drugs for injection should be avoided. When storing, keep it out of reach of children, avoid direct sunlight, and store in a cool, dry place. Additionally, do not transfer it to another container, and prevent misuse.

• Anorexia
• gastrointestinal disorders
• nausea
• drowsiness
• vomiting
• hyperhidrosis
• dizziness
• tachycardia
• palpitations
• thirst

This medication should be stored in a sealed container to prevent air or moisture from entering, preferably at room temperature between 1°C and 30°C. Proper storage will maintain the medication's efficacy and prevent deterioration.

Appearance

A colorless, odorless transparent solution contained in a colorless and transparent ampule injection.

Package unit

2mL×20 ampules