Rosumin 20 mg (Rosuvastatin Calcium)

Adult dosage

This medication can be administered at any time of the day regardless of meals. The initial dosage is 5 mg taken once daily, with a maintenance dosage of 10 mg once daily, which is sufficient for most patients. The maintenance dosage should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response every 4 weeks or more, with a maximum increase up to 20 mg daily.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the daily dosage ranges from 5 mg to 20 mg administered once daily. Dosing should be adjusted based on individual patient needs every 4 weeks or more.

This medication should not be used in certain patients. For example, patients allergic to any components of this medication or those with active liver diseases should not take it. Patients with muscle disorders or severe renal impairment also should avoid taking this medication. Women who are pregnant or breastfeeding, and women of childbearing age who do not use appropriate contraception should also avoid this medication. This medication contains lactose, and it is important for individuals with lactose intolerance or related genetic disorders to refrain from taking it. When taking this medication, caution is advised if consuming alcohol excessively or if there is a history of liver disease. It is advisable to have regular liver function tests to monitor one’s condition. Patients with hypothyroidism or nephrotic syndrome must treat the underlying cause of their disorders before taking this medication. If symptoms of muscle pain or weakness occur, inform healthcare professionals immediately and undergo necessary tests. Particularly, if muscle enzyme levels significantly rise, treatment may need to be halted. Rarely, severe skin reactions or liver damage can occur in some patients when taking this medication; therefore, if skin rashes, jaundice, or severe fatigue appear, discontinue the medication immediately and consult a physician. This medication may interact with other drugs, so it is essential to inform healthcare providers about any other medications being taken. Caution is particularly needed when taken with specific antivirals, immunosuppressants, antifungals, certain antibiotics, and fibrate class medications. Women who are pregnant or planning to become pregnant must consult a specialist before deciding whether to take this medication, and breastfeeding mothers should avoid it as well. In case of overdose, since there is no specific antidote, one should visit a medical institution immediately for appropriate treatment and evaluation. This medication is not known to significantly affect driving or equipment operation, but caution is advised as dizziness may occur.

Serious side effects

Allergic reactions including urticaria, angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, respiratory distress, ophthalmoplegia, jaundice, Stevens-Johnson syndrome, severe allergic reactions, severe skin reactions, significant edema, severe myasthenia, acute renal failure, oliguria, severe liver damage, and hyperbilirubinemia. Serious allergic reactions, immune-mediated myopathy, severe neurological symptoms (e.g., seizures, altered consciousness).

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• asthenia
• increased blood sugar

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best kept at room temperature between 1°C and 30°C. Storing it this way will help maintain the drug's efficacy for a longer time.

Appearance

Pink, round film-coated tablet

Package unit

28 tablets/Alu-Alu, 30 tablets/bottle, 300 tablets/bottle