Antiplatelet Tablet (Clopidogrel Hydrogen Sulfate)

Adult dosage

○ Adults 1. For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer clopidogrel 75 mg orally once daily. 2. For patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), initiate treatment with a loading dose of 300 mg of this medicine once on the day treatment is started, followed by a maintenance dose of 75 mg orally once daily. Aspirin 75 ～ 325 mg should be coadministered with this medicine once daily. 3. For patients with atrial fibrillation, administer 75 mg of this medicine orally once daily. Aspirin 75 ～ 100 mg should be coadministered with this medicine once daily. ○ Patients with renal impairment: Treatment experience in patients with renal impairment is limited. ○ Patients with hepatic impairment: Treatment experience in patients with moderate liver disease and a bleeding diathesis is limited. This medicine may be administered with or without food.

This medication helps to prevent platelets from clumping together, facilitating better blood flow. However, individuals who genetically have reduced function of the enzyme CYP2C19, which activates this medication, may not experience its full effectiveness. In such cases, it is advisable to consult a physician to change the treatment method or use another medication. Furthermore, taking other medications that enhance the effect of this drug may increase the risk of bleeding, so it is best not to use them together. Patients who are allergic to this medication or have severe bleeding, patients with significant liver damage, nursing women, lactose intolerant patients, or individuals with allergies to soybean oil, peanuts, or beans should not take this medication. Patients at high risk of bleeding or those scheduled for surgery must consult a doctor before taking this drug, and they may be advised to stop taking it 5-7 days before surgery. This medication may increase the risk of bleeding when taken with other bleeding risk medications, so caution is necessary. If bleeding symptoms are suspected during the course of treatment, notify healthcare professionals immediately, and it is important to regularly check blood tests to assess the risk of bleeding. Possible side effects of this medication include bleeding, reduction in blood cell counts, gastrointestinal disturbances, skin rashes, and, rarely, serious blood disorders; hence, consult a physician immediately if any unusual symptoms occur. If pregnant or nursing, it is essential to discuss the use of this medication with a doctor. Overdosage may increase the risk of bleeding, so it is crucial to adhere to the prescribed dosage, particularly for children, the elderly, and patients with compromised kidney or liver function. This medication has not been confirmed to be safe and effective for use in children, so it is advisable to avoid using it. While taking this medication, inform healthcare providers of interactions with other medications or supplements that may increase the risk of bleeding. Finally, this medication should be stored out of the reach of children, and it is advisable not to transfer it to other containers.

• Hemorrhage
• gastrointestinal bleeding
• hospitalization required hemorrhage
• purpura
• contusion
• hematoma
• epistaxis
• hematoma
• hematuria
• intraocular hemorrhage

This medication should be stored in a closed container to prevent air or moisture ingress and maintained at a temperature between 1 to 30 degrees Celsius (34 to 86 degrees Fahrenheit). This helps maintain the medication's effectiveness for a longer period.

Appearance

Pink, round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle