Cefuroxime Axetil Tablet 250 mg

Adult dose

For optimal absorption, take after meals. Administer 250mg twice daily. (Most infections) Administer 500mg twice daily. (Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms) Administer 250mg twice daily. (Urinary tract infections) Administer 1g as a single dose. (Uncomplicated gonorrhea) Administer 500mg twice daily for 14 days (10~21 days). (Lyme disease) For the treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this medicine should be administered for 7~10 days. 3. Patients with renal impairment Cefuroxime is eliminated primarily by the kidneys. To compensate for delayed elimination in patients with significantly impaired renal function, dose reduction of cefuroxime is recommended as follows. ≥ 30 mL/min/1.73㎡ | 1.4 - 2.4 | No dose adjustment required (standard dose: 125mg-500mg per dose, twice daily) 10 - 29 mL/min/1.73㎡ | 4.6 | Administer the standard single dose every 24 hours < 10 mL/min/1.73㎡ | 16.8 | Administer the standard single dose every 48 hours Patients receiving hemodialysis | 2 - 4 | Administer an additional standard single dose at the end of each dialysis session

Child dose

Children aged 12 years and older: Administer 250mg twice daily. (Most infections) Children aged 12 years and older: Administer 500mg twice daily. (Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms) Children aged 12 years and older: Administer 250mg twice daily. (Urinary tract infections) Children aged 12 years and older: Administer 1g as a single dose. (Uncomplicated gonorrhea) Children aged 12 years and older: Administer 500mg twice daily for 14 days (10~21 days). (Lyme disease) Infants and children under 12 years: Administer 125mg twice daily. (Most infections) Children aged 2 years and older: Administer 250mg twice daily. (Otitis media, severe infections) Infants and children under 12 years: Administer 250mg twice daily for 14 days (10~21 days). (Lyme disease) There is insufficient experience with use in infants under 3 months of age. This medicine must not be divided and is therefore not suitable for treating patients who cannot swallow tablets, such as young infants and children.

This medication should not be used in patients allergic to cephalosporin antibiotics. It should be used cautiously in patients with a history of allergies to penicillin or other beta-lactam antibiotics, patients with allergic constitutions, and patients with severely impaired kidney function. Caution must be exercised when administering this medication to the elderly or patients in poor general condition, or to patients who have difficulty taking oral medications, and monitoring is necessary as there may be symptoms of vitamin K deficiency. Generally, this medication has many mild and transient side effects, which may include skin rashes, urticaria, itching, nausea, diarrhea, headache, and dizziness. Rarely, serious skin reactions, blood abnormalities, liver dysfunction, or kidney dysfunction may occur, so if any unusual symptoms arise, consultation with a physician should be sought immediately. During the administration of this medication, it should only be used for the minimum duration necessary to prevent the development of bacterial resistance, and treatment efficacy should be regularly evaluated. If discomfort, dizziness, difficulty breathing, or rash occurs during administration, the treatment should be stopped immediately and medical personnel should be informed. Overgrowth of organisms such as Candida may occur due to antibiotic use, so caution is advised in long-term use. If gastrointestinal symptoms such as diarrhea or abdominal pain worsen, the possibility of pseudomembranous colitis should be considered, and treatment should be stopped and additional examinations should be conducted. The safety of this medication during pregnancy or lactation has not been established, so it should be used cautiously under a physician's judgment. In children, particularly infants under 3 months of age, the safety has not been confirmed, and caution is warranted; syrup formulation is recommended as breaking the tablet may lead to a strong bitter taste. The elderly may experience side effects more easily due to decreased bodily function, so dosage and intervals should be adjusted and carefully monitored. This medication may affect kidney function, so regular kidney function tests are required, and if abnormalities are detected, administration should be halted. Drug interactions may occur when taken with other medications; caution is especially needed when combined with diuretics, aminoglycoside antibiotics, probenecid, and antacids. Dizziness may occur when driving or operating machinery, so attention should be exercised. In case of overdose, central nervous system symptoms such as seizures may appear, and drug concentrations can be reduced by hemodialysis or peritoneal dialysis. This medication should be stored out of reach of children and kept in its original container for safety.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• anemia
• decrease in hemoglobin
• decrease in hematocrit
• hemolytic anemia

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is essential to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and prevents degradation.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle - 30 tablets/bottle, 30 tablets/bottle, 100 tablets/bottle - 100 tablets/bottle