Seltirion Clarithromycin Tablet 500mg

Adult dosage

○ Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This drug should not be used in patients with certain medications or conditions. For example, it should not be administered to patients who are allergic to any component contained in this drug or who have had a hypersensitive reaction to certain antibiotics, patients with heart rhythm abnormalities, or severe liver or kidney impairment. It is also advisable for pregnant or breastfeeding women to avoid this medication. Special caution should be taken when administering this drug to patients with liver or kidney impairment, heart disease, elderly patients, and those taking other specific medications. This drug can cause various side effects, so if symptoms such as skin rash, difficulty breathing, indigestion, or neurological symptoms occur during use, it is essential to consult a doctor immediately. Especially if severe allergic reactions, liver function abnormalities, or signs of kidney function decrease occur, immediate discontinuation of dosing and appropriate treatment must be obtained. This drug has a high potential for interactions with other medications, so it is essential to inform medical staff of any other medications being taken, and caution must be taken as side effects or changes in efficacy may occur due to drug interactions. When pregnant or breastfeeding, this medication should be avoided, and if it must be used, it should be done carefully after consulting a specialist. When administering this drug to children or the elderly, careful monitoring of dosage adjustment and side effect occurrence is required. Overdose may cause gastrointestinal disturbances or psychiatric symptoms, so adherence to the prescribed dosage is critical, and care should be taken to avoid exceeding the dosage. This drug should be stored in a light-resistant container, and refrigeration should be avoided.

Shock, anaphylactic symptoms, difficulty breathing, convulsions, flushing, rash, itching, hives, skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, indigestion, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, epigastric pain, form of convulsions, dry mouth, transient teeth discoloration, pancreatitis, increased amylase, taste disturbance, loss of appetite, constipation, discoloration of stool, membrane colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavior changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, elevated liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, loss of appetite, jaundice, dark urine, itching, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, elevated myoglobin in blood, elevated myoglobin in urine, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, tinnitus, auditory disability, hypoglycemia, purpuric rash, acute generalized eruptive pustulosis, muscle cramps, musculoskeletal rigidity, myopathy, elevated blood urea, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This drug is sensitive to light and should be stored in a light-resistant container. Additionally, it is recommended to store it at room temperature between 15 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle