Clarithromycin Tablet 250 mg

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) per dose, administered twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer this medicine to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) per dose twice daily. In this case, it should be co-administered with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Co-administer 500mg (potency) of this medicine 3 times daily and omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and administer omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This medication should not be administered to patients with certain medications or health conditions. For example, patients who are allergic to any ingredients contained in this drug, those with certain heart diseases, serious liver diseases, or severely impaired kidney function should not use it. Additionally, it is safer for pregnant or breastfeeding women to avoid taking this medication. Extra caution is needed for young children or patients with central nervous system infections, and serious side effects may occur when combined with certain medications, so consultation with a physician is essential. Patients with weakened liver or kidney function, elderly patients with heart disease, etc., should use this drug with particular caution, and dosage adjustments may be necessary if needed. While taking this medication, various side effects such as allergic reactions, gastrointestinal disturbances, liver function abnormalities, kidney problems, skin rashes, and central nervous system abnormalities may occur, so inform the healthcare provider immediately if symptoms arise. Moreover, this drug has a high potential for interactions with other medications; thus, if you are currently taking any other medications, you must inform your healthcare provider, particularly if they include heart-related medications, anticoagulants, certain antibiotics, sedatives, or statins. Long-term or repeated use may lead to resistance; therefore, strict adherence to the dosage and duration recommended by the physician is necessary. Lastly, this medication may affect driving or operating machinery, so caution should be exercised when engaging in these activities during treatment.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbances, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, venous thrombophlebitis at injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine color abnormality

This medication is sensitive to light, so it should be stored in a light-blocking container. Furthermore, it is important to maintain its effectiveness by storing it at room temperature between 15 degrees and 30 degrees.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle