Amoxicillin/Clavulanate 375 mg (Amoxicillin-Potassium Clavulanate (2:1))

Adult dose

For adults and children over 12 years old or weighing 40 kg or more, the dosage is 250 mg/125 mg of amoxicillin/clavulanate, taken orally three times a day every 8 hours. In cases of severe and respiratory infections, the dosage may be increased to 500 mg/125 mg. In cases of renal impairment, dosage should be adjusted based on creatinine clearance. For those with a clearance of 10-30 mL/min, take 250 mg/125 mg every 12 hours.

Child dose

For children over 12 years old or weighing 40 kg or more, the dosage is the same as in adults: 250 mg/125 mg for each dose, taken orally three times a day every 8 hours, and in cases of severe and respiratory infections, increase to 500 mg/125 mg.

This drug is a penicillin antibiotic and should not be used in certain patients. In particular, patients who have had an allergy to this drug or beta-lactam drugs, those with infectious mononucleosis or lymphocytic leukemia, and those who have had liver dysfunction or jaundice due to this drug should avoid its use. Patients with impaired liver or kidney function should use this drug with special caution, and those with allergic predispositions, elderly patients, or those with gastrointestinal disorders should also take it carefully. During treatment, adverse reactions such as diarrhea, abdominal pain, skin rash, itching, and difficulty breathing may occur; if such symptoms arise, consult a physician immediately. Rarely, symptoms of liver dysfunction, blood disorders, kidney function abnormalities, and central nervous system dysfunction may occur, so regular check-ups may be necessary. Additionally, this drug may interact with other drugs, so it is essential to inform your doctor or pharmacist if you are taking other medications. Pregnant or nursing women should carefully assess the risks and benefits with their doctor if the use of this drug is necessary. It is not recommended for children, especially those under 12 years of age or those weighing less than 40 kg. For elderly patients, caution is needed during administration due to an increased risk of side effects from decreased body functions. In cases of overdose, gastrointestinal symptoms, kidney abnormalities, and allergic reactions may occur, so you should immediately notify medical personnel and receive appropriate emergency care. This drug should be stored in a sealed container to avoid moisture, and kept at a cool temperature below 25 degrees Celsius, avoiding direct sunlight.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reaction, high fever with severe rash, blisters, skin peeling, pain in oral/eye mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with coughing and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver dysfunction (jaundice), sudden and severe symptoms

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This drug is kept in a sealed container to avoid moisture, and it should be stored at a cool temperature between 1 and 25 degrees Celsius. Proper storage will preserve the effectiveness of the medication for a long time and ensure safe use.

Appearance

Oval film-coated tablets, white or almost white

Package unit

100 tablets/PTP (10 tablets x 10 tablets)