Rosuvastatin Calcium Tablets 20 mg

Adult dosage

Administer 5 mg once daily as an initial dose at any time of the day regardless of meals. If greater LDL cholesterol reduction is needed, maintain with a dosage of 10 mg once daily, adjusting at intervals of 4 weeks or more. A maximum of 20 mg per day may be increased.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia aged 10 to 17 years, administer a dose of 5 mg to 20 mg once daily. The dosage should be adjusted at intervals of 4 weeks or more, and for children under 10 years of age, safety and efficacy have not been established.

This drug should not be used in certain patients. For example, patients who are allergic to any component of this medication, those with severely impaired liver function, patients with muscle disorders, those taking certain immunosuppressants, patients with severe kidney dysfunction, pregnant or breastfeeding women, and fertile women who are not using adequate contraception should not be administered this drug. Additionally, patients at high risk for muscle-related disorders or with specific genetic conditions, as well as those sensitive to lactose contained in this drug, should be cautious. This drug can affect liver function, so patients who consume alcohol heavily or have a history of liver disease should undergo regular liver function tests before and during treatment. If symptoms such as muscle pain or weakness occur, the doctor should be informed immediately, and if blood tests show elevated indicators of muscle injury along with these symptoms, discontinuation of the medication may be necessary. It is also advisable to discontinue this medication in cases of severe illness or acute conditions. Rarely, this drug may cause severe skin reactions or liver damage, so if symptoms like skin rash, jaundice, or severe fatigue appear, it is important to stop taking it immediately and consult healthcare personnel. This drug may interact with other medications, so it is essential to inform the doctor or pharmacist of any other medications being taken, particularly when using specific antiviral agents, immunosuppressants, antibiotics, or fibrate drugs. Pregnant or breastfeeding women should not use this medication, and women of childbearing age should employ proper contraceptive methods. There is no specific antidote for overdose, so treatment should be symptom-based, and liver function and muscle injury indicators should be tested. This drug may cause side effects such as dizziness, requiring caution when driving or operating machinery. Finally, Asian patients may demonstrate higher concentrations of this drug in the body, necessitating dose adjustments.

Serious side effects

Allergic reactions including urticaria and angioedema, pancreatitis, myopathy, rhabdomyolysis, immune-mediated necrotizing myopathy, severe muscular weakness, ophthalmoplegia, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, acute renal failure, oliguria, edema, interstitial lung disease, fatal and non-fatal liver failure, severe headache, liver function test abnormalities

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

Store this medication in a tightly sealed container to prevent exposure to air or moisture, and keep it at a safe temperature between 1°C and 30°C. This helps maintain the drug's effectiveness.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle