Kairoutin Tablet 10mg (Rosuvastatin Calcium)

Adult dosage

Administer once daily at a starting dose of 5 milligrams at any time of the day regardless of meals, and if necessary, adjust to a maintenance dose of 10 milligrams once daily, with a maximum increase to 20 milligrams once daily. Dose adjustments should be made at intervals of 4 weeks or more based on LDL-cholesterol levels, treatment goals, and patient response.

Children's dosage

For pediatric patients aged 10 to 17 years, administer once daily at a dose ranging from 5 milligrams to 20 milligrams, adjusted according to the recommended treatment goals and with intervals of 4 weeks or more.

This drug should not be used in certain patients. For example, patients who are allergic to any of the components, those with severe liver dysfunction, muscle diseases, or severe kidney dysfunction should not take this medication. Women who are pregnant or breastfeeding, and women of childbearing potential not using appropriate contraception should also not take this medication, and women of childbearing age should be fully informed of the potential risks to pregnancy and the fetus. This drug requires special caution in patients at high risk of muscle damage, such as those with moderately or severely impaired renal function, hypothyroidism, those with a family history of muscle disease or past muscle toxic reactions, alcoholics, and those taking specific drugs concurrently. Moreover, since this drug contains lactose, patients with lactose intolerance or related genetic disorders should not take it. Before and during treatment with this drug, liver function tests should be conducted regularly to check liver status. Patients with a history of liver disease or excessive alcohol consumption require extra caution. If symptoms such as myalgia, muscle weakness, or cramps occur, inform a physician immediately, and in severe cases, discontinue the medication. Additionally, it is advisable to avoid tests for muscle damage after vigorous exercise. This drug may interact with other medications; therefore, if other medications are being taken, patients must inform their doctor or pharmacist and consult them. Particular care should be taken when combined with certain antiviral agents, immunosuppressants, antibiotics, or fibrates, as the risk of muscle damage may increase. Pregnant or breastfeeding women, or women planning to become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. In case of overdose, as there is no specific antidote, treatment should be symptomatic while monitoring liver function and markers of muscle damage. This drug does not significantly impact the ability to drive or operate machinery; however, patients should be cautious as dizziness may occur. If severe skin reactions or allergic symptoms occur while taking this drug, it should be stopped immediately, and medical advice should be sought.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, severe swelling, chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug rash with eosinophilia and systemic symptoms (DRESS), jaundice, acute renal failure, oliguria, thrombocytopenia, increased transaminases, hepatitis, myopathy, rhabdomyolysis, immune-mediated necrotizing myopathy, polyneuropathy, amnesia, peripheral neuropathy, severe muscle weakness, respiratory issues

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is essential to maintain the storage temperature between 1 and 30 degrees Celsius to preserve the medication's effectiveness.

Appearance

Pink round film-coated tablet

Package unit

30 tablets (15 tablets/PTP*2), 30 tablets/bottle, 100 tablets/bottle