Vesicore Tablet 10 mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If needed, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. The dosage and administration should be adjusted for the following patients. 1. Patients with renal impairment No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dose adjustment is necessary in patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh class B), and do not exceed 5mg once daily. 3. Patients receiving strong cytochrome P450 3A4 (CYP3A4) inhibitors For patients receiving ketoconazole or other strong CYP3A4 inhibitors (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This drug is used to relieve bladder hyperactivity and should not be used in patients with difficulty urinating, severe gastrointestinal disorders, myasthenia gravis, or eye diseases such as glaucoma. Patients with severely impaired liver or kidney function, those undergoing dialysis, or those allergic to this medication or its ingredients should also avoid using it. Caution should be exercised with patients who have gastrointestinal obstruction diseases or are at risk of blocking the bladder outlet, and the dosage should be reduced in patients with moderately impaired liver or kidney function. While taking this medication, side effects such as dry mouth, constipation, blurred vision, urinary retention, and dry eyes may occur, especially with higher doses, these symptoms may occur more frequently. Rarely, angioedema or allergic reactions may occur, and if swelling of the face or neck or difficulty breathing occurs, discontinue the medication immediately and consult a healthcare professional. This drug is metabolized by specific enzymes in the liver, so if taken with strong enzyme inhibitors such as certain antifungal agents, the drug concentration may increase, requiring dosage adjustment. Safety during pregnancy has not been established, so caution is needed, and breastfeeding women should avoid using this medication as it may affect the baby through breast milk. The safety and efficacy in children have not been confirmed, and it should not be administered to them. In case of overdose, symptoms such as headache, dizziness, drowsiness, and blurred vision can occur, and appropriate treatment should be sought immediately. Finally, there is a risk of accidents while driving or operating machinery due to drowsiness or blurred vision while taking this medication, so caution is advised.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• angioneurotic edema
• nausea

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius to ensure the efficacy and safety of the drug over time.

Appearance

Bright pink round film-coated tablet

Package unit

100 tablets (10 tablets/PTP x 10), 30 tablets/bottle, 100 tablets/bottle