Optus Ceftriaxone Sodium Hydrate Injection 1 Gram

Adult administration

For adults and children over 12 years old, administer 1–2 g (potency) of ceftriaxone once daily via intravenous or intramuscular injection. For infections caused by severe pathogens or pathogens with moderate susceptibility, the dose can be increased to 4 g (potency) once daily. In the treatment of gonorrhea, a single intramuscular injection of 250 mg (potency) is recommended. For the prevention of infections before and after surgery, it is advisable to administer 1–2 g (potency) once 30–90 minutes prior to surgery.

Child administration

For infants and children under 12 years old, administer 20–80 mg (potency) per kg of body weight once daily. For children over 50 kg, administer the adult dose, intravenously at 50 mg (potency) or more.

This drug must not be mixed or administered simultaneously with calcium-containing solutions or other medications. In particular, there is a risk of serious side effects if precipitates occur when administered together with calcium in newborns. Patients with hypersensitivity to this medication or those allergic to cephalosporins or penicillin antibiotics should not use it, and neither should premature infants or newborns with issues related to bilirubin binding. Precautions are needed for patients with a history of allergies, poor kidney function, or elderly individuals, and dosage adjustment or modification of the administration interval may be necessary. During administration, regular tests such as blood tests, liver function tests, and kidney function tests should be conducted to monitor for adverse reactions. Although rare, severe allergic reactions, pseudomembranous colitis, interstitial pneumonia, blood disorders, kidney abnormalities, central nervous system effects, and serious skin reactions can occur, and symptoms should be reported to healthcare professionals immediately. This medication should be administered with caution to pregnant women or nursing mothers, and the potential effects on the fetus or newborn should be carefully considered. Interactions with other medications should be checked during administration, particularly with diuretics, aminoglycoside antibiotics, and vitamin K antagonists, which necessitate caution. This drug may cause dizziness, which might require caution while driving or operating machinery. The prepared solution should be used promptly, and care should be taken regarding temperature and duration during storage.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• itching
• headache
• dizziness
• loose stools

This medication should be stored in a sealed container to prevent air or moisture from entering, at room temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the drug's efficacy and prevents degradation.

Appearance

A colorless transparent vial filled with white to pale yellow crystalline powder

Package unit

10 vials (1g*10)