Medication info
Cravocin 250 mg (Levofloxacin Hemihydrate)

Cravocin 250 mg (Levofloxacin Hemihydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›256.15mg / 1 tablet
Manufacturer / importer
대웅바이오(주)
Appearance
Light pink rectangular film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201607197 · Approved 2016.12.21 · Insurance code 694001320

Summary

Main use
Treatment of bacterial infections such as complicated skin and soft tissue infections and community-acquired pneumonia
Who takes it
Adults
Adult dose
Typically, for adults, Levofloxacin is administered orally once daily at a dose of 250 to 750 mg. 1. Patients with normal kidney function (creatinine clearance over 80 mL/min) - Complicated skin and soft tissue infections: 750 mg at 24-hour intervals for 10 to 14 days - Community-acquired pneumonia: 500 mg at 24-hour intervals for 7 days - Acute bacterial exacerbations of chronic bronchitis: administered for 7 days - Acute sinusitis: 10

Ingredients

Manufacturer
대웅바이오(주)

Efficacy & effects

Treatment of bacterial infections such as complicated skin and soft tissue infections and community-acquired pneumonia

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbations of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • uncomplicated urinary tract infections
View approved original text

This drug is effective against various bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and is used to treat multiple infectious diseases such as complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, acute sinusitis, and urinary tract infections. However, due to the nature of fluoroquinolone drugs, there is a risk of serious side effects; thus, it should be used only when no alternative treatments are available for acute bacterial sinusitis, exacerbations of chronic bronchitis, uncomplicated urinary tract infections, and complicated skin and soft tissue infections. It is to be used safely and helps in the treatment of infections.

How to take

Adult dose

Typically, for adults, Levofloxacin is administered orally once daily at a dose of 250 to 750 mg. 1. Patients with normal kidney function (creatinine clearance over 80 mL/min) - Complicated skin and soft tissue infections: 750 mg at 24-hour intervals for 10 to 14 days - Community-acquired pneumonia: 500 mg at 24-hour intervals for 7 days - Acute bacterial exacerbations of chronic bronchitis: administered for 7 days - Acute sinusitis: 10

Precautions

This drug can cause tendon-related side effects such as tendonitis and tendon rupture, so if there is pain or inflammation in the tendon, use should be discontinued immediately. There is a risk of peripheral neuropathy or central nervous system issues, as well as worsening of myasthenia gravis, so if these symptoms appear, discontinuation and consultation with a doctor is necessary. It is recommended not to use this drug in patients with severe myasthenia gravis. This drug is to be used only for specific bacterial infections and is best administered only when no other treatment options are available. Caution is especially needed for elderly patients, patients with impaired kidney function, and those using corticosteroids, as the risk of tendon rupture increases. This drug may increase the risk of seizures, so patients with a history of epilepsy or convulsions should use it with caution. Additionally, this medication should not be administered to patients with hypersensitivity to it or similar drugs, pregnant or nursing women, adolescents under 18 years old, or patients with epilepsy. During treatment, care should be taken to avoid excessive exposure to sunlight or artificial ultraviolet light, and if symptoms of skin rash or hypersensitivity appear, use should be discontinued immediately. Symptoms such as dizziness, drowsiness, and visual disturbances may occur; therefore, caution should be taken while driving or operating machinery. This drug may interact with other medications, so especially when used in conjunction with antacids, iron preparations, calcium supplements, theophylline, anticoagulants, and diabetes medications, consultation with a physician or pharmacist is advisable. Due to the possibility of blood sugar disturbances, diabetic patients should carefully monitor their blood sugar levels. Patients with heart issues or aortic aneurysms, and those with heart valve abnormalities should consult a doctor before using this medication, and if relevant symptoms appear, immediate medical attention is needed. In case of overdose, there is a risk of central nervous system symptoms and heart problems, so immediate treatment and monitoring are required. This drug is not safe for use in children and adolescents of growth age. Elderly individuals require dose adjustments and monitoring due to the possibility of elevated drug concentration from impaired kidney function.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound fatigue, sudden and severe headache, lightning headache, seizures, altered consciousness, vision abnormalities, paralysis, urination

Mild side effects

  • Nausea
  • diarrhea
  • vaginitis
  • insomnia
  • abdominal pain
  • bloating
  • itching
  • dizziness
  • rash
  • dyspepsia
Show 23 more
  • stomatitis
  • glossitis
  • thirst
  • constipation
  • vomiting
  • fungal infections
  • genital itching
  • headache
  • neurosis
  • erythematous rash
  • decreased appetite
  • drowsiness
  • agitation
  • thirst
  • tremors
  • allergic reactions
  • palpitations
  • increased BUN and serum creatinine
  • elevated liver enzymes (AST/ALT)
  • increased ALP
  • γ-GTP
  • total bilirubin
  • white blood cells

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature of 1 to 30 degrees Celsius (room temperature). This will help to preserve the drug's efficacy for an extended period.

Appearance and packaging

Appearance

Light pink rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.