Rosuvastatin 20 mg (Rosuvastatin Calcium)

Adult dosage

Administer once daily at any time of the day, regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is 10 mg once daily. The dose can be adjusted at intervals of 4 weeks or more as needed, with a maximum daily dose of 20 mg.

Children's dosage

For pediatric patients aged 10 to 17 years, administer 5 mg to 20 mg once daily, adjusting the dose individually at intervals of 4 weeks or more according to treatment goals. Safety for pediatric patients under 10 years has not been established.

This medication should not be used in certain patients. For example, it should not be taken by patients who are allergic to this medication, have severe liver dysfunction, have muscle-related diseases, have severely impaired renal function, or by pregnant or breastfeeding women. Additionally, high-dose use is prohibited in patients at high risk for muscle disorders. This medication contains lactose, so caution is advised in patients with lactose intolerance. Patients who consume large amounts of alcohol or have a history of liver disease should frequently monitor liver function tests before taking this medication. If symptoms of muscle pain or weakness appear, inform the medical staff immediately, and in severe cases, discontinue the medication. Patients with poor kidney function or hypothyroidism should treat these conditions before starting the medication. This medication can rarely cause severe skin reactions or liver damage, so if skin rashes or jaundice occur, it should be discontinued immediately. This medication may interact with other medications, so patients must inform their medical staff of any other drugs they are taking, particularly some antibiotics, antivirals, immunosuppressants, etc. Women who may become pregnant should use appropriate contraceptives and must not take this medication during pregnancy. There is no specific antidote for overdose, so treatment should be symptomatic, and liver function and muscle enzyme tests are necessary. While this medication does not significantly impact driving or operating machinery, patients should be cautious as dizziness may occur.

Serious side effects

• Hives, angioedema including hypersensitivity reactions → severe allergic reactions
• Stevens-Johnson syndrome, eosinophilia and systemic symptoms-associated drug reaction syndrome (DRESS) → severe skin adverse reactions
• Breathing difficulties, cough, and respiratory problems including shortness of breath
• Skin or eyes turning yellow (jaundice), hepatitis, jaundice → liver dysfunction (jaundice)
• Sudden, severe headache, seizures, altered consciousness, visual disturbances, paralysis and other severe symptoms

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• hematuria

Store this medication in a tightly closed container to protect it from air and moisture, at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness for a longer duration.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/PTP [(15 tablets/PTP × 2)]